The Enzyme Database

Table of Contents

The enzymes in this section of the database are organized as you would find them in the Enzyme-Nomenclature book. Click [+] to expand, and [–] to collapse, any section. Clicking on a heading will open popup window with information on that class, subclass or sub-subclass.

For a fully expanded list of the classes, subclasses and sub-subclasses, click here

[+subclass]. [+sub-subclass]. [+serial]

EC 1 []   
    EC 1.1  [+]      
    EC 1.2  [+]      
    EC 1.3  [+]      
    EC 1.4  [+]      
    EC 1.5  [+]      
    EC 1.6  [+]      
    EC 1.7  [+]      
    EC 1.8  [+]      
    EC 1.9  [+]      
    EC 1.10  [+]      
    EC 1.11  [+]      
    EC 1.12  [+]      
    EC 1.13  [+]      
    EC 1.14  []      
        EC 1.14.1       [+]    With NADH or NADPH as one donor (deleted sub-subclass) 
        EC 1.14.2       [+]    With ascorbate as one donor (deleted sub-subclass) 
        EC 1.14.3       [+]    With reduced pteridine as one donor (deleted sub-subclass) 
        EC 1.14.11       [+]    With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor 
        EC 1.14.12       [+]    With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor 
        EC 1.14.13       []    With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor 
                EC 1.14.13.1                      salicylate 1-monooxygenase 
                EC 1.14.13.2                      4-hydroxybenzoate 3-monooxygenase 
                EC 1.14.13.3                      4-hydroxyphenylacetate 3-monooxygenase. Now EC 1.14.14.9, 4-hydroxyphenylacetate 3-monooxygenase. 
                EC 1.14.13.4                      melilotate 3-monooxygenase 
                EC 1.14.13.5                      imidazoleacetate 4-monooxygenase 
                EC 1.14.13.6                      orcinol 2-monooxygenase 
                EC 1.14.13.7                      phenol 2-monooxygenase (NADPH) 
                EC 1.14.13.8                      flavin-containing monooxygenase 
                EC 1.14.13.9                      kynurenine 3-monooxygenase 
                EC 1.14.13.10                      2,6-dihydroxypyridine 3-monooxygenase 
                EC 1.14.13.11                      trans-cinnamate 4-monooxygenase 
                EC 1.14.13.12                      benzoate 4-monooxygenase 
                EC 1.14.13.13                      calcidiol 1-monooxygenase. Now classified as EC 1.14.15.18, calcidiol 1-monooxygenase 
                EC 1.14.13.14                      trans-cinnamate 2-monooxygenase 
                EC 1.14.13.15                      cholestanetriol 26-monooxygenase. Now EC 1.14.15.15, cholestanetriol 26-monooxygenase. 
                EC 1.14.13.16                      cyclopentanone monooxygenase 
                EC 1.14.13.17                      cholesterol 7α-monooxygenase. Now EC 1.14.14.23, cholesterol 7α-monooxygenase 
                EC 1.14.13.18                      4-hydroxyphenylacetate 1-monooxygenase 
                EC 1.14.13.19                      taxifolin 8-monooxygenase 
                EC 1.14.13.20                      2,4-dichlorophenol 6-monooxygenase 
                EC 1.14.13.21                      flavonoid 3′-monooxygenase 
                EC 1.14.13.22                      cyclohexanone monooxygenase 
                EC 1.14.13.23                      3-hydroxybenzoate 4-monooxygenase 
                EC 1.14.13.24                      3-hydroxybenzoate 6-monooxygenase 
                EC 1.14.13.25                      methane monooxygenase (soluble) 
                EC 1.14.13.26                      phosphatidylcholine 12-monooxygenase. Now classified as EC 1.14.18.4, phosphatidylcholine 12-monooxygenase. 
                EC 1.14.13.27                      4-aminobenzoate 1-monooxygenase 
                EC 1.14.13.28                      3,9-dihydroxypterocarpan 6a-monooxygenase 
                EC 1.14.13.29                      4-nitrophenol 2-monooxygenase 
                EC 1.14.13.30                      leukotriene-B4 20-monooxygenase 
                EC 1.14.13.31                      2-nitrophenol 2-monooxygenase 
                EC 1.14.13.32                      albendazole monooxygenase 
                EC 1.14.13.33                      4-hydroxybenzoate 3-monooxygenase [NAD(P)H] 
                EC 1.14.13.34                      leukotriene-E4 20-monooxygenase 
                EC 1.14.13.35                      anthranilate 3-monooxygenase (deaminating) 
                EC 1.14.13.36                      5-O-(4-coumaroyl)-D-quinate 3′-monooxygenase 
                EC 1.14.13.37                      methyltetrahydroprotoberberine 14-monooxygenase 
                EC 1.14.13.38                      anhydrotetracycline 6-monooxygenase 
                EC 1.14.13.39                      nitric-oxide synthase (NADPH) 
                EC 1.14.13.40                      anthraniloyl-CoA monooxygenase 
                EC 1.14.13.41                      tyrosine N-monooxygenase. Now EC 1.14.14.36, tyrosine N-monooxygenase 
                EC 1.14.13.42                      hydroxyphenylacetonitrile 2-monooxygenase. The activity is covered by EC 1.14.13.68, 4-hydroxyphenylacetaldehyde oxime monooxygenase, that performs the two consecutive reactions in the conversion of (Z)-4-hydroxyphenylacetaldehyde oxime to (S)-4-hydroxymandelonitrile 
                EC 1.14.13.43                      questin monooxygenase 
                EC 1.14.13.44                      2-hydroxybiphenyl 3-monooxygenase 
                EC 1.14.13.45                      CMP-N-acetylneuraminate monooxygenase. Now EC 1.14.18.2, CMP-N-acetylneuraminate monooxygenase 
                EC 1.14.13.46                      (-)-menthol monooxygenase 
                EC 1.14.13.47                      (S)-limonene 3-monooxygenase 
                EC 1.14.13.48                      (S)-limonene 6-monooxygenase. Now classified as EC 1.14.14.51, (S)-limonene 6-monooxygenase 
                EC 1.14.13.49                      (S)-limonene 7-monooxygenase. Now classified as EC 1.14.14.52, (S)-limonene 7-monooxygenase 
                EC 1.14.13.50                      pentachlorophenol monooxygenase 
                EC 1.14.13.51                      6-oxocineole dehydrogenase 
                EC 1.14.13.52                      isoflavone 3′-hydroxylase 
                EC 1.14.13.53                      4′-methoxyisoflavone 2′-hydroxylase 
                EC 1.14.13.54                      ketosteroid monooxygenase 
                EC 1.14.13.55                      protopine 6-monooxygenase 
                EC 1.14.13.56                      dihydrosanguinarine 10-monooxygenase 
                EC 1.14.13.57                      dihydrochelirubine 12-monooxygenase 
                EC 1.14.13.58                      benzoyl-CoA 3-monooxygenase 
                EC 1.14.13.59                      L-lysine N6-monooxygenase (NADPH) 
                EC 1.14.13.60                      27-hydroxycholesterol 7α-monooxygenase. Now included with EC 1.14.13.100, 25-hydroxycholesterol 7α-hydroxylase 
                EC 1.14.13.61                      2-hydroxyquinoline 8-monooxygenase 
                EC 1.14.13.62                      4-hydroxyquinoline 3-monooxygenase 
                EC 1.14.13.63                      3-hydroxyphenylacetate 6-hydroxylase 
                EC 1.14.13.64                      4-hydroxybenzoate 1-hydroxylase 
                EC 1.14.13.65                       2-hydroxyquinoline 8-monooxygenase 
                EC 1.14.13.66                      2-hydroxycyclohexanone 2-monooxygenase 
                EC 1.14.13.67                      quinine 3-monooxygenase 
                EC 1.14.13.68                      4-hydroxyphenylacetaldehyde oxime monooxygenase. Now EC 1.14.14.37, 4-hydroxyphenylacetaldehyde oxime monooxygenase 
                EC 1.14.13.69                      alkene monooxygenase 
                EC 1.14.13.70                      sterol 14α-demethylase 
                EC 1.14.13.71                      N-methylcoclaurine 3′-monooxygenase 
                EC 1.14.13.72                      methylsterol monooxygenase. Now classified as EC 1.14.18.9, methylsterol monooxygenase 
                EC 1.14.13.73                      tabersonine 16-hydroxylase 
                EC 1.14.13.74                      7-deoxyloganin 7-hydroxylase 
                EC 1.14.13.75                      vinorine hydroxylase 
                EC 1.14.13.76                      taxane 10β-hydroxylase 
                EC 1.14.13.77                      taxane 13α-hydroxylase 
                EC 1.14.13.78                      ent-kaurene oxidase 
                EC 1.14.13.79                      ent-kaurenoic acid oxidase 
                EC 1.14.13.80                      (R)-limonene 6-monooxygenase. Now classified as EC 1.14.14.53, (R)-limonene 6-monooxygenase 
                EC 1.14.13.81                      magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase 
                EC 1.14.13.82                      vanillate monooxygenase 
                EC 1.14.13.83                      precorrin-3B synthase 
                EC 1.14.13.84                      4-hydroxyacetophenone monooxygenase 
                EC 1.14.13.85                      glyceollin synthase 
                EC 1.14.13.86                      2-hydroxyisoflavanone synthase. This enzyme was classified on the basis of an incorrect reaction. The activity is covered by EC 1.14.13.136, 2-hydroxyisoflavanone synthase 
                EC 1.14.13.87                      licodione synthase 
                EC 1.14.13.88                      flavanoid 3′,5′-hydroxylase 
                EC 1.14.13.89                      isoflavone 2′-hydroxylase 
                EC 1.14.13.90                      zeaxanthin epoxidase. Now EC 1.14.15.21, zeaxanthin epoxidase 
                EC 1.14.13.91                      deoxysarpagine hydroxylase 
                EC 1.14.13.92                      phenylacetone monooxygenase 
                EC 1.14.13.93                      (+)-abscisic acid 8′-hydroxylase 
                EC 1.14.13.94                      lithocholate 6β-hydroxylase 
                EC 1.14.13.95                      7α-hydroxycholest-4-en-3-one 12α-hydroxylase. Now EC 1.14.18.8, 7α-hydroxycholest-4-en-3-one 12α-hydroxylase 
                EC 1.14.13.96                      5β-cholestane-3α,7α-diol 12α-hydroxylase 
                EC 1.14.13.97                      taurochenodeoxycholate 6α-hydroxylase 
                EC 1.14.13.98                      cholesterol 24-hydroxylase. Now EC 1.14.14.25, cholesterol 24-hydroxylase  
                EC 1.14.13.99                      24-hydroxycholesterol 7α-hydroxylase. Now EC 1.14.14.26, 24-hydroxycholesterol 7α-hydroxylase 
                EC 1.14.13.100                      25/26-hydroxycholesterol 7α-hydroxylase. Now classified as EC 1.14.14.29, 25/26-hydroxycholesterol 7α-hydroxylase 
                EC 1.14.13.101                      senecionine N-oxygenase 
                EC 1.14.13.102                      psoralen synthase 
                EC 1.14.13.103                      8-dimethylallylnaringenin 2′-hydroxylase 
                EC 1.14.13.104                      (+)-menthofuran synthase 
                EC 1.14.13.105                      monocyclic monoterpene ketone monooxygenase 
                EC 1.14.13.106                      epi-isozizaene 5-monooxygenase 
                EC 1.14.13.107                      limonene 1,2-monooxygenase 
                EC 1.14.13.108                      abieta-7,13-diene hydroxylase 
                EC 1.14.13.109                      abieta-7,13-dien-18-ol hydroxylase 
                EC 1.14.13.110                      geranylgeraniol 18-hydroxylase 
                EC 1.14.13.111                      methanesulfonate monooxygenase (NADH) 
                EC 1.14.13.112                      3-epi-6-deoxocathasterone 23-monooxygenase 
                EC 1.14.13.113                      FAD-dependent urate hydroxylase 
                EC 1.14.13.114                      6-hydroxynicotinate 3-monooxygenase 
                EC 1.14.13.115                      angelicin synthase 
                EC 1.14.13.116                      geranylhydroquinone 3′′-hydroxylase 
                EC 1.14.13.117                      isoleucine N-monooxygenase, Now EC 1.14.14.39, isoleucine N-monooxygenase 
                EC 1.14.13.118                      valine N-monooxygenase. Now EC 1.14.14.38, valine N-monooxygenase 
                EC 1.14.13.119                      5-epiaristolochene 1,3-dihydroxylase 
                EC 1.14.13.120                      costunolide synthase 
                EC 1.14.13.121                      premnaspirodiene oxygenase 
                EC 1.14.13.122                      chlorophyllide-a oxygenase 
                EC 1.14.13.123                      germacrene A hydroxylase 
                EC 1.14.13.124                      phenylalanine N-monooxygenase, now classified as EC 1.14.14.40, phenylalanine N-monooxygenase 
                EC 1.14.13.125                      tryptophan N-monooxygenase 
                EC 1.14.13.126                      vitamin D3 24-hydroxylase. Now EC 1.14.15.16, vitamin D3 24-hydroxylase 
                EC 1.14.13.127                      3-(3-hydroxyphenyl)propanoate hydroxylase 
                EC 1.14.13.128                      7-methylxanthine demethylase 
                EC 1.14.13.129                      β-carotene 3-hydroxylase 
                EC 1.14.13.130                      pyrrole-2-carboxylate monooxygenase 
                EC 1.14.13.131                      dimethyl-sulfide monooxygenase 
                EC 1.14.13.132                      squalene monooxygenase. Now EC 1.14.14.17, squalene monooxygenase 
                EC 1.14.13.133                      pentalenene oxygenase 
                EC 1.14.13.134                      β-amyrin 11-oxidase 
                EC 1.14.13.135                      1-hydroxy-2-naphthoate hydroxylase 
                EC 1.14.13.136                      2-hydroxyisoflavanone synthase 
                EC 1.14.13.137                      indole-2-monooxygenase 
                EC 1.14.13.138                      indolin-2-one monooxygenase 
                EC 1.14.13.139                      3-hydroxyindolin-2-one monooxygenase 
                EC 1.14.13.140                      2-hydroxy-1,4-benzoxazin-3-one monooxygenase 
                EC 1.14.13.141                      cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming] 
                EC 1.14.13.142                      3-ketosteroid 9α-monooxygenase 
                EC 1.14.13.143                      ent-isokaurene C2-hydroxylase 
                EC 1.14.13.144                      9β-pimara-7,15-diene oxidase 
                EC 1.14.13.145                      ent-cassa-12,15-diene 11-hydroxylase 
                EC 1.14.13.146                      taxoid 14β-hydroxylase 
                EC 1.14.13.147                      taxoid 7β-hydroxylase 
                EC 1.14.13.148                      trimethylamine monooxygenase 
                EC 1.14.13.149                      phenylacetyl-CoA 1,2-epoxidase 
                EC 1.14.13.150                      α-humulene 10-hydroxylase 
                EC 1.14.13.151                      linalool 8-monooxygenase 
                EC 1.14.13.152                      geraniol 8-hydroxylase 
                EC 1.14.13.153                      (+)-sabinene 3-hydroxylase 
                EC 1.14.13.154                      erythromycin 12-hydroxylase 
                EC 1.14.13.155                      α-pinene monooxygenase 
                EC 1.14.13.156                      1,8-cineole 2-endo-monooxygenase 
                EC 1.14.13.157                      1,8-cineole 2-exo-monooxygenase 
                EC 1.14.13.158                      amorpha-4,11-diene 12-monooxygenase 
                EC 1.14.13.159                      vitamin D 25-hydroxylase. Now EC 1.14.14.24, vitamin D 25-hydroxylase 
                EC 1.14.13.160                      (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase 
                EC 1.14.13.161                      (+)-camphor 6-exo-hydroxylase 
                EC 1.14.13.162                      2,5-diketocamphane 1,2-monooxygenase 
                EC 1.14.13.163                      6-hydroxy-3-succinoylpyridine 3-monooxygenase 
                EC 1.14.13.164                      carotenoid isomerooxygenase. The enzyme was discovered at the public-review stage to have been misclassified and so was withdrawn. See EC 1.13.11.65, carotenoid isomerooxygenase 
                EC 1.14.13.165                      nitric-oxide synthase [NAD(P)H]. Now classified as EC 1.14.14.47, nitric-oxide synthase (flavodoxin) 
                EC 1.14.13.166                      4-nitrocatechol 4-monooxygenase 
                EC 1.14.13.167                      4-nitrophenol 4-monooxygenase 
                EC 1.14.13.168                      indole-3-pyruvate monooxygenase 
                EC 1.14.13.169                      sphinganine C4-monooxygenase. Now EC 1.14.18.5, sphingolipid C4-monooxygenase 
                EC 1.14.13.170                      pentalenolactone D synthase 
                EC 1.14.13.171                      neopentalenolactone D synthase 
                EC 1.14.13.172                      salicylate 5-hydroxylase 
                EC 1.14.13.173                      11-oxo-β-amyrin 30-oxidase 
                EC 1.14.13.174                      averantin hydroxylase 
                EC 1.14.13.175                      aflatoxin B synthase 
                EC 1.14.13.176                      tryprostatin B 6-hydroxylase 
                EC 1.14.13.177                      fumitremorgin C monooxygenase 
                EC 1.14.13.178                      methylxanthine N1-demethylase 
                EC 1.14.13.179                      methylxanthine N3-demethylase 
                EC 1.14.13.180                      aklavinone 12-hydroxylase 
                EC 1.14.13.181                      13-deoxydaunorubicin hydroxylase 
                EC 1.14.13.182                      2-heptyl-3-hydroxy-4(1H)-quinolone synthase 
                EC 1.14.13.183                      dammarenediol 12-hydroxylase 
                EC 1.14.13.184                      protopanaxadiol 6-hydroxylase 
                EC 1.14.13.185                      pikromycin synthase 
                EC 1.14.13.186                      20-oxo-5-O-mycaminosyltylactone 23-monooxygenase 
                EC 1.14.13.187                      L-evernosamine nitrososynthase 
                EC 1.14.13.188                      6-deoxyerythronolide B hydroxylase 
                EC 1.14.13.189                      5-methyl-1-naphthoate 3-hydroxylase 
                EC 1.14.13.190                      ferruginol synthase 
                EC 1.14.13.191                      ent-sandaracopimaradiene 3-hydroxylase 
                EC 1.14.13.192                      oryzalexin E synthase 
                EC 1.14.13.193                      oryzalexin D synthase 
                EC 1.14.13.194                      phylloquinone ω-hydroxylase 
                EC 1.14.13.195                      L-ornithine N5-monooxygenase (NADPH) 
                EC 1.14.13.196                      L-ornithine N5-monooxygenase [NAD(P)H] 
                EC 1.14.13.197                      dihydromonacolin L hydroxylase 
                EC 1.14.13.198                      monacolin L hydroxylase 
                EC 1.14.13.199                      docosahexaenoic acid ω-hydroxylase 
                EC 1.14.13.200                      tetracenomycin A2 monooxygenase-dioxygenase 
                EC 1.14.13.201                      β-amyrin 28-monooxygenase 
                EC 1.14.13.202                      methyl farnesoate epoxidase 
                EC 1.14.13.203                      farnesoate epoxidase 
                EC 1.14.13.204                      long-chain acyl-CoA ω-monooxygenase 
                EC 1.14.13.205                      long-chain fatty acid ω-monooxygenase 
                EC 1.14.13.206                      laurate 7-monooxygenase 
                EC 1.14.13.207                      ipsdienol synthase. Now EC 1.14.14.31, ipsdienol synthase 
                EC 1.14.13.208                      benzoyl-CoA 2,3-epoxidase 
                EC 1.14.13.209                      salicyloyl-CoA 5-hydroxylase 
                EC 1.14.13.210                      4-methyl-5-nitrocatechol 5-monooxygenase 
                EC 1.14.13.211                      rifampicin monooxygenase 
                EC 1.14.13.212                      1,3,7-trimethyluric acid 5-monooxygenase 
                EC 1.14.13.213                      bursehernin 5′-monooxygenase 
                EC 1.14.13.214                      (–)-4′-demethyl-deoxypodophyllotoxin 4-hydroxylase 
                EC 1.14.13.215                      protoasukamycin 4-monooxygenase 
                EC 1.14.13.216                      asperlicin C monooxygenase 
                EC 1.14.13.217                      protodeoxyviolaceinate monooxygenase 
                EC 1.14.13.218                      5-methylphenazine-1-carboxylate 1-monooxygenase 
                EC 1.14.13.219                      resorcinol 4-hydroxylase (NADPH) 
                EC 1.14.13.220                      resorcinol 4-hydroxylase (NADH) 
                EC 1.14.13.221                      cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming] 
                EC 1.14.13.222                      aurachin C monooxygenase/isomerase 
                EC 1.14.13.223                      3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase 
                EC 1.14.13.224                      violacein synthase 
                EC 1.14.13.225                      F-actin monooxygenase 
                EC 1.14.13.226                      acetone monooxygenase (methyl acetate-forming) 
                EC 1.14.13.227                      propane 2-monooxygenase 
                EC 1.14.13.228                      jasmonic acid 12-hydroxylase 
                EC 1.14.13.229                      tert-butyl alcohol monooxygenase 
                EC 1.14.13.230                      butane monooxygenase (soluble) 
                EC 1.14.13.231                      tetracycline 11a-monooxygenase 
                EC 1.14.13.232                      6-methylpretetramide 4-monooxygenase 
                EC 1.14.13.233                      4-hydroxy-6-methylpretetramide 12a-monooxygenase 
                EC 1.14.13.234                      5a,11a-dehydrotetracycline 5-monooxygenase 
                EC 1.14.13.235                      indole-3-acetate monooxygenase 
                EC 1.14.13.236                      toluene 4-monooxygenase 
                EC 1.14.13.237                      aliphatic glucosinolate S-oxygenase 
                EC 1.14.13.238                      dimethylamine monooxygenase 
        EC 1.14.14       [+]    With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor 
        EC 1.14.15       [+]    With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor 
        EC 1.14.16       [+]    With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor 
        EC 1.14.17       [+]    With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor 
        EC 1.14.18       [+]    With another compound as one donor, and incorporation of one atom of oxygen into the other donor 
        EC 1.14.19       [+]    With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water 
        EC 1.14.20       [+]    With 2-oxoglutarate as one donor, and the other dehydrogenated 
        EC 1.14.21       [+]    With NADH or NADPH as one donor, and the other dehydrogenated 
        EC 1.14.99       [+]    Miscellaneous 
    EC 1.15  [+]      
    EC 1.16  [+]      
    EC 1.17  [+]      
    EC 1.18  [+]      
    EC 1.19  [+]      
    EC 1.20  [+]      
    EC 1.21  [+]      
    EC 1.22  [+]      
    EC 1.23  [+]      
    EC 1.97  [+]      
    EC 1.98  [+]      
    EC 1.99  [+]      
EC 2 [+]   
EC 3 [+]   
EC 4 [+]   
EC 5 [+]   
EC 6 [+]   


© 2001-2017 IUBMB