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Accepted name: 5-methyl-1-naphthoate 3-hydroxylase
Reaction: 5-methyl-1-naphthoate + NADPH + H
+ O + = 3-hydroxy-5-methyl-1-naphthoate + NADP 2 + H + O
For diagram of the azinomycin biosynthesis (part of pathway),
Other name(s): AziB1
Systematic name: 5-methyl-1-naphthoate,NADPH:oxygen oxidoreductase (3-hydroxylating)
Comments: The enzyme from the bacterium
Streptomyces sahachiroi is involved in the biosynthesis of 3-methoxy-5-methyl-1-naphthoate, a component of of the the antitumor antibiotic azinomycin B.
Links to other databases:
BRENDA, EXPASY, KEGG, MetaCyc
Ding, W., Deng, W., Tang, M., Zhang, Q., Tang, G., Bi, Y. and Liu, W. Biosynthesis of 3-methoxy-5-methyl naphthoic acid and its incorporation into the antitumor antibiotic azinomycin B.
Mol. Biosyst. 6 (2010) 1071–1081. [ DOI] [PMID: 20485749]
[EC 22.214.171.124 created 2014]
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