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Your query returned 1 entry. Printable version
EC | 1.14.14.87 | ||||||||||
Accepted name: | 2-hydroxyisoflavanone synthase | ||||||||||
Reaction: | (1) liquiritigenin + O2 + [reduced NADPH—hemoprotein reductase] = 2,4′,7-trihydroxyisoflavanone + H2O + [oxidized NADPH—hemoprotein reductase] (2) (2S)-naringenin + O2 + [reduced NADPH—hemoprotein reductase] = 2,4′,5,7-tetrahydroxyisoflavanone + H2O + [oxidized NADPH—hemoprotein reductase] |
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For diagram of daidzein biosynthesis, click here | |||||||||||
Glossary: | liquiritigenin = 4′,7-dihydroxyflavanone (2S)-naringenin = 4′,5,7-dihydroxyflavanone 2,4′,5,7-tetrahydroxyisoflavanone = 2-hydroxy-2,3-dihydrogenistein |
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Other name(s): | CYP93C; IFS; isoflavonoid synthase | ||||||||||
Systematic name: | liquiritigenin, [reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (hydroxylating, aryl migration) | ||||||||||
Comments: | A cytochrome P-450 (heme thiolate) protein found in plants. The reaction involves the migration of the 2-phenyl group of the flavanone to the 3-position of the isoflavanone. The 2-hydroxyl group is derived from the oxygen molecule. EC 4.2.1.105, 2-hydroxyisoflavanone dehydratase, acts on the products with loss of water and formation of genistein and daidzein, respectively. | ||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||
References: |
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