|
|
| ID |
Date/Time |
EC/Citation Key |
Table |
Field |
Changed From |
Changed To |
| 931 |
2005-12-11 10:12:40 |
2.6.1.81 |
entry |
comments |
|
A pyridoxal-phosphate protein. Also acts on N2-acetyl-L-ornithine and L-ornithine, but more slowly [3]. In Pseudomonas aeruginosa, the arginine-inducible succinylornithine transaminase, acetylornithine transaminase (EC 2.6.1.11) and ornithine transaminase (EC 2.6.1.13) activities are catalysed by the same enzyme, but this is not the case in all species [5]. This is the third enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine [1]. This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA. The five enzymes involved in this pathway are EC 2.3.1.109 (arginine N-succinyltransferase), EC 3.5.3.23 (N-succinylarginine dihydrolase), EC 2.6.1.81 (succinylornithine transaminase), EC 1.2.1.71 (succinylglutamate semialdehyde dehydrogenase) and EC 3.5.1.96 (succinylglutamate desuccinylase) [3, 6]. Of the five enzymes involved in arginine catabolism, this is the only one that is also involved in ornithine catabolism [4]. |
| 932 |
2005-12-11 10:12:40 |
2.6.1.81 |
entry |
links |
|
|
| 933 |
2005-12-11 10:12:40 |
2.6.1.81 |
entry |
class |
|
2 |
| 934 |
2005-12-11 10:12:40 |
2.6.1.81 |
entry |
subclass |
|
6 |
| 935 |
2005-12-11 10:12:40 |
2.6.1.81 |
entry |
subsubclass |
|
1 |
| 936 |
2005-12-11 10:12:40 |
2.6.1.81 |
entry |
serial |
|
81 |
| 938 |
2005-12-11 10:12:40 |
2.6.1.81 |
entry |
diagram |
|
|
| 939 |
2005-12-11 10:12:40 |
2.6.1.81 |
entry |
cas_num |
|
|
| 949 |
2005-12-11 10:12:40 |
2.6.1.81 |
entry |
glossary |
|
|
| 974 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
glossary |
|
|
| 964 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
cas_num |
|
|
| 963 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
diagram |
|
|
| 961 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
serial |
|
71 |
| 960 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
subsubclass |
|
1 |
| 959 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
subclass |
|
2 |
| 958 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
class |
|
1 |
| 957 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
links |
|
|
| 956 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
comments |
|
This is the fourth enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine [1]. This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA. The five enzymes involved in this pathway are EC 2.3.1.109 (arginine N-succinyltransferase), EC 3.5.3.23 (N-succinylarginine dihydrolase), EC 2.6.1.11 (succinylornithine transaminase), EC 1.2.1.71 (succinylglutamate semialdehyde dehydrogenase) and EC 3.5.1.96 (succinylglutamate desuccinylase) [3,6]. |
| 955 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
sys_name |
|
N2-succinyl-L-glutamate 5-semialdehyde:NAD+ oxidoreductase |
| 954 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
other_names |
|
succinylglutamic semialdehyde dehydrogenase; N-succinylglutamate 5-semialdehyde dehydrogenase; SGSD; AruD; AstD |
| 953 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
reaction |
|
N2-succinyl-L-glutamate 5-semialdehyde + NAD+ = N2-succinyl-L-glutamate + NADH + 2 H+ |
| 952 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
common_name |
|
succinylglutamate-semialdehyde dehydrogenase |
| 951 |
2005-12-11 10:17:06 |
1.2.1.71 |
entry |
ec_num |
|
1.2.1.71 |
| 1001 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
glossary |
|
|
| 991 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
cas_num |
|
|
| 990 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
diagram |
|
|
| 988 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
serial |
|
95 |
| 987 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
subsubclass |
|
1 |
| 986 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
subclass |
|
5 |
| 985 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
class |
|
3 |
| 984 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
links |
|
|
| 983 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
comments |
|
Forms part of the oxidative pyrimidine-degrading pathway in some microorganisms, along with EC 1.17.99.3 (uracil/thymine dehydrogenase) and EC 3.5.2.1 (barbiturase). |
| 982 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
sys_name |
|
3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming) |
| 981 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
other_names |
|
ureidomalonase |
| 980 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
reaction |
|
3-oxo-3-ureidopropanoate + H2O = malonate + urea |
| 979 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
common_name |
|
N-malonylurea hydrolase |
| 978 |
2005-12-11 10:24:07 |
3.5.1.95 |
entry |
ec_num |
|
3.5.1.95 |
| 1011 |
2005-12-11 10:26:42 |
3.5.2.1 |
entry |
glossary |
|
barbiturate = 6-hydroxyuracil |
| 1005 |
2005-12-11 10:26:42 |
3.5.2.1 |
entry |
comments |
|
Contains zinc and is specific for barbiturate as substrate [3]. Forms part of the oxidative pyrimidine-degrading pathway in some microorganisms, along with EC 1.17.99.3 (uracil/thymine dehydrogenase) and 3.5.1.95 (N-malonylurea hydrolase). It was previously thought that the end-products of the reaction were malonate and urea but this has since been disproved [2]. May be involved in the regulation of pyrimidine metabolism, along with EC 2.4.2.9, uracil phosphoribosyltransferase. |
| 1004 |
2005-12-11 10:26:42 |
3.5.2.1 |
entry |
sys_name |
barbiturate amidohydrolase |
barbiturate amidohydrolase (3-oxo-3-ureidopropanoate-forming) |
| 1003 |
2005-12-11 10:26:42 |
3.5.2.1 |
entry |
reaction |
barbiturate + H2O = malonate + urea |
barbiturate + H2O = 3-oxo-3-ureidopropanoate |
| 1018 |
2005-12-11 10:32:16 |
4.1.1.21 |
entry |
comments |
|
While this is the reaction that occurs in vertebrates during purine biosynthesis, two enzymes are required to carry out the same reaction in Escherichia coli, namely EC 6.3.4.18, (5-(carboxyamino)imidazole ribonucleotide synthase and EC 5.4.99.18, 5-(carboxyamino)imidazole ribonucleotide mutase [3]. 5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole is not a substrate. |
| 1017 |
2005-12-11 10:32:16 |
4.1.1.21 |
entry |
sys_name |
1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase |
| 1016 |
2005-12-11 10:32:16 |
4.1.1.21 |
entry |
other_names |
5-phosphoribosyl-5-aminoimidazole carboxylase; 5-amino-1-ribosylimidazole 5-phosphate carboxylase; AIR carboxylase |
5-phosphoribosyl-5-aminoimidazole carboxylase; 5-amino-1-ribosylimidazole 5-phosphate carboxylase; AIR carboxylase; 1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase |
| 1052 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
glossary |
|
|
| 1042 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
cas_num |
|
|
| 1041 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
diagram |
|
|
| 1039 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
serial |
|
18 |
| 1038 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
subsubclass |
|
99 |
| 1037 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
subclass |
|
4 |
| 1036 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
class |
|
5 |
| 1035 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
links |
|
|
| 1034 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
comments |
|
In Escherichia coli, this enzyme, along with EC 6.3.4.18, 5-(carboxyamino)imidazole ribonucleotide synthase, is required to carry out the single reaction catalysed by EC 4.1.1.21, phosphoribosylaminoimidazole carboxylase, in vertebrates. In the absence of EC 6.3.2.6, phosphoribosylaminoimidazolesuccinocarboxamide synthase, the reaction is reversible [3]. The substrate is readily converted into 5-amino-1-(5-phospho-D-ribosyl)imidazole by non-enzymic decarboxylation [3]. |
| 1033 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
sys_name |
|
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase |
| 1032 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
other_names |
|
N5-CAIR mutase; PurE; N5-carboxyaminoimidazole ribonucleotide mutase |
| 1031 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
reaction |
|
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate |
| 1030 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
common_name |
|
5-(carboxyamino)imidazole ribonucleotide mutase |
| 1029 |
2005-12-11 10:37:20 |
5.4.99.18 |
entry |
ec_num |
|
5.4.99.18 |
| 1059 |
2005-12-11 10:45:38 |
6.3.2.6 |
entry |
comments |
|
Forms part of the purine biosynthesis pathway. |
| 1058 |
2005-12-11 10:45:38 |
6.3.2.6 |
entry |
other_names |
phosphoribosylaminoimidazole-succinocarboxamide synthetase |
phosphoribosylaminoimidazole-succinocarboxamide synthetase; PurC; SAICAR synthetase; 4-(N-succinocarboxamide)-5-aminoimidazole synthetase; 4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase; SAICARs; 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase |
| 1089 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
glossary |
|
|
| 1079 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
cas_num |
|
|
| 1078 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
diagram |
|
|
| 1076 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
serial |
|
18 |
| 1075 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
subsubclass |
|
4 |
| 1074 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
subclass |
|
3 |
| 1073 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
class |
|
6 |
| 1072 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
links |
|
|
| 1071 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
comments |
|
In Escherichia coli, this enzyme, along with EC 5.4.99.18, 5-(carboxyamino)imidazole ribonucleotide mutase, is required to carry out the single reaction catalysed by EC 4.1.1.21, phosphoribosylaminoimidazole carboxylase, in vertebrates. Belongs to the ATP grasp protein superfamily [3]. Carboxyphosphate is the putative acyl phosphate intermediate. Involved in the late stages of purine biosynthesis. |
| 1070 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
sys_name |
|
5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming) |
| 1069 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
other_names |
|
N5-CAIR synthetase; N5-carboxyaminoimidazole ribonucleotide synthetase; PurK |
| 1068 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
reaction |
|
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole + HCO3- = ADP + phosphate + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole |
| 1067 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
common_name |
|
5-(carboxyamino)imidazole ribonucleotide synthase |
| 1066 |
2005-12-11 10:48:42 |
6.3.4.18 |
entry |
ec_num |
|
6.3.4.18 |
| 1097 |
2005-12-11 11:08:28 |
4.2.1.60 |
entry |
reaction |
(3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl-carrier protein] (or 3-decenoyl-[acyl-carrier protein]) + H2O |
(1) (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = trans-2-decenoyl-[acyl-carrier protein] + H2O;;(2) (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = cis-3-decenoyl-[acyl-carrier protein] + H2O |
| 1098 |
2005-12-11 11:08:28 |
4.2.1.60 |
entry |
other_names |
D-3-hydroxydecanoyl-[acyl-carrier protein] dehydratase; 3-hydroxydecanoyl-acyl carrier protein dehydrase; 3-hydroxydecanoyl-acyl carrier protein dehydratase; beta-hydroxydecanoyl thioester dehydrase; beta-hydroxydecanoate dehydrase |
D-3-hydroxydecanoyl-[acyl-carrier protein] dehydratase; 3-hydroxydecanoyl-acyl carrier protein dehydrase; 3-hydroxydecanoyl-acyl carrier protein dehydratase; beta-hydroxydecanoyl thioester dehydrase; beta-hydroxydecanoate dehydrase; β-hydroxydecanoyl thiol ester dehydrase; FabA; beta-hydroxyacyl-acyl carrier protein dehydratase; HDDase; beta-hydroxyacyl-ACP dehydrase |
| 1106 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
ec_num |
|
5.3.3.14 |
| 1107 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
common_name |
|
trans-2-decenoyl-ACP isomerase |
| 1108 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
reaction |
|
trans-2-decenoyl-[acyl-carrier protein] = cis-3-decenoyl-[acyl-carrier protein] |
| 1109 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
other_names |
|
beta-hydroxydecanoyl thioester dehydrase; trans-2-cis-3-decenoyl-ACP isomerase; trans-2,cis-3-decenoyl-ACP isomerase; FabM |
| 1110 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
sys_name |
|
decenoyl-[acyl-carrier protein] Delta2-trans-Delta3-cis-isomerase |
| 1111 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
comments |
|
ame: decenoyl-[acyl-carrier protein] Delta2-trans-Delta3-cis-isomerase
Comments: While the enzyme from Escherichia coli is highly specific for the 10-carbon enoyl-ACP, the enzyme from Streptococcus pneumoniae can also use the 12-carbon enoyl-ACP as substrate in vitro but not 14- or 16-carbon enoyl-ACPs [3]. ACP can be replaced by either CoA or N-acetylcysteamine thioesters. The cis-3-enoyl product is required to form unsaturated fatty acids, such as palmitoleic acid and cis-vaccenic acid, in dissociated (or type II) fatty acid biosynthesis. |
| 1112 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
links |
|
|
| 1113 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
class |
|
5 |
| 1114 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
subclass |
|
3 |
| 1115 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
subsubclass |
|
3 |
| 1116 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
serial |
|
14 |
| 1118 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
diagram |
|
|
| 1119 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
cas_num |
|
|
| 1129 |
2005-12-11 11:15:40 |
5.3.3.14 |
entry |
glossary |
|
|
| 1132 |
2005-12-11 11:20:03 |
2.3.1.41 |
entry |
common_name |
3-oxoacyl-[acyl-carrier-protein] synthase |
beta-ketoacyl-ACP synthase I |
| 1133 |
2005-12-11 11:20:03 |
2.3.1.41 |
entry |
other_names |
beta-ketoacyl synthetase; beta-ketoacyl-ACP synthetase; beta-ketoacyl-acyl carrier protein synthetase; beta-ketoacyl-[acyl carrier protein] synthase; beta-ketoacylsynthase; condensing enzyme; 3-ketoacyl-acyl carrier protein synthase; fatty acid condensing enzyme; acyl-malonyl(acyl-carrier-protein)-condensing enzyme; beta-ketoacyl acyl carrier protein synthase |
beta-ketoacyl synthetase; beta-ketoacyl-ACP synthetase; beta-ketoacyl-acyl carrier protein synthetase; beta-ketoacyl-[acyl carrier protein] synthase; beta-ketoacylsynthase; condensing enzyme; 3-ketoacyl-acyl carrier protein synthase; fatty acid condensing enzyme; acyl-malonyl(acyl-carrier-protein)-condensing enzyme; beta-ketoacyl acyl carrier protein synthase; 3-oxoacyl-[acyl-carrier-protein] synthase; 3-oxoacyl:ACP synthase I; KASI; KAS I; FabF1; FabB |
| 1134 |
2005-12-11 11:20:03 |
2.3.1.41 |
entry |
comments |
|
This enzyme is responsible for the chain-elongation step of dissociated (type II) fatty acid biosynthesis. Escherichia coli mutants that lack this enzyme are deficient in unsaturated fatty acids. The enzyme can use fatty acyl thioesters of ACP (C2 to C16) as substrates, as well as fatty acyl thioesters of Co-A (C4 to C16) [4]. The substrate specificity is very similar to that of EC 2.3.1.178, beta-ketoacyl-ACP synthase II, with the exception that the latter enzyme is far more active with palmitoleoyl-ACP (C16Delta9) as substrate, allowing the organism to regulate its fatty-acid composition with changes in temperature [4,5]. |
| 1141 |
2005-12-12 04:35:40 |
3.6.3.45 |
entry |
common_name |
|
steroid-transporting ATPase |
| 1142 |
2005-12-12 04:35:40 |
3.6.3.45 |
entry |
reaction |
|
ATP + H2O + steroidin = ADP + phosphate + steroidout |
| 1143 |
2005-12-12 04:35:40 |
3.6.3.45 |
entry |
other_names |
|
pleiotropic-drug-resistance protein; PDR protein |
| 1144 |
2005-12-12 04:35:40 |
3.6.3.45 |
entry |
sys_name |
|
ATP phosphohydrolase (steroid-exporting) |
| 1145 |
2005-12-12 04:35:40 |
3.6.3.45 |
entry |
comments |
|
ABC-type (ATP-binding cassette-type) ATPase, characterised by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. A yeast protein that exports a variety of xenobiotics, especially steroids. |
| 1168 |
2005-12-12 07:04:01 |
2.3.1.177 |
entry |
other_names |
L-2,4-diaminobutyrate acetyltransferase; L-2,4-diaminobutanoate acetyltransferase; EctA; diaminobutyric acid acetyltransferase; DABA acetyltransferase; 2,4-diaminobutanoate acetyltransferase; DAB acetyltransferase; DABAcT |
BIS |
| 1170 |
2005-12-12 07:04:01 |
2.3.1.177 |
entry |
comments |
Requires Na+ or K+ for maximal activity [3]. Ornithine, lysine, aspartate, and alpha-, beta- and gamma-aminobutyrate cannot act as substrates [3]. However, acetyl-CoA can be replaced by propanoyl-CoA, although the reaction proceeds more slowly [3]. Forms part of the ectoine-biosynthesis pathway, the other enzymes involved being EC 2.6.1.76, diaminobutyrate—2-oxoglutarate transaminase and EC 4.2.1.108, ectoine synthase. |
A polyketide synthase that is involved in the production of the phytoalexin aucuparin. 2-Hydroxybenzoyl-CoA can also act as substrate but it leads to the derailment product 2-hydroxybenzoyltriacetic acid lactone. This enzyme uses the same starter substrate as EC 2.3.1.51, benzophenone synthase. |
| 1169 |
2005-12-12 07:04:01 |
2.3.1.177 |
entry |
sys_name |
acetyl-CoA:L-2,4-diaminobutanoate acetyltransferase |
malonyl-CoA:benzoyl-CoA malonyltransferase |
| 1167 |
2005-12-12 07:04:01 |
2.3.1.177 |
entry |
reaction |
acetyl-CoA + L-2,4-diaminobutanoate = CoA + N-acetyl-L-2,4-diaminobutyrate |
3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydrobiphenyl + 4 CO2 |
| 1166 |
2005-12-12 07:04:01 |
2.3.1.177 |
entry |
common_name |
diaminobutyrate acetyltransferase |
biphenyl synthase |
| 1176 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
ec_num |
|
2.3.1.178 |
| 1177 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
common_name |
|
diaminobutyrate acetyltransferase |
| 1178 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
reaction |
|
acetyl-CoA + L-2,4-diaminobutanoate = CoA + N-acetyl-L-2,4-diaminobutyrate |
| 1179 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
other_names |
|
L-2,4-diaminobutyrate acetyltransferase; L-2,4-diaminobutanoate acetyltransferase; EctA; diaminobutyric acid acetyltransferase; DABA acetyltransferase; 2,4-diaminobutanoate acetyltransferase; DAB acetyltransferase; DABAcT |
| 1180 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
sys_name |
|
acetyl-CoA:L-2,4-diaminobutanoate acetyltransferase |
| 1181 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
comments |
|
Requires Na+ or K+ for maximal activity [3]. Ornithine, lysine, aspartate, and alpha-, beta- and gamma-aminobutyrate cannot act as substrates [3]. However, acetyl-CoA can be replaced by propanoyl-CoA, although the reaction proceeds more slowly [3]. Forms part of the ectoine-biosynthesis pathway, the other enzymes involved being EC 2.6.1.76, diaminobutyrate—2-oxoglutarate transaminase and EC 4.2.1.108, ectoine synthase. |
| 1182 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
links |
|
|
| 1183 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
class |
|
2 |
| 1184 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
subclass |
|
3 |
| 1185 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
subsubclass |
|
1 |
| 1186 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
serial |
|
178 |
| 1188 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
diagram |
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|
| 1189 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
cas_num |
|
|
| 1199 |
2005-12-12 07:05:26 |
2.3.1.178 |
entry |
glossary |
|
|
| 1201 |
2005-12-12 07:06:11 |
2.6.1.76 |
entry |
comments |
A pyridoxal-phosphate protein that requires potassium for activity [4]. Involved in the formation of 1,3-diaminopropane in Haemophilus influenzae and Acinetobacter baumannii. A product of the ddc gene that also encodes L-2,4-diaminobutyrate decarboxylase in Acinetobacter baumannii. Differs from EC 2.6.1.46 diaminobutyrate-pyruvate transaminase, which has pyruvate as the amino-group acceptor. This is the first enzyme in the ectoine biosynthesis pathway, the other enzymes involved being EC 2.5.1.74, diaminobutyrate acetyltransferase and 4.2.1.108, ectoine synthase [3,4]. |
A pyridoxal-phosphate protein that requires potassium for activity [4]. Involved in the formation of 1,3-diaminopropane in Haemophilus influenzae and Acinetobacter baumannii. A product of the ddc gene that also encodes L-2,4-diaminobutyrate decarboxylase in Acinetobacter baumannii. Differs from EC 2.6.1.46 diaminobutyrate-pyruvate transaminase, which has pyruvate as the amino-group acceptor. This is the first enzyme in the ectoine biosynthesis pathway, the other enzymes involved being EC 2.5.1.78, diaminobutyrate acetyltransferase and 4.2.1.108, ectoine synthase [3,4]. |
| 1203 |
2005-12-12 07:06:54 |
4.2.1.108 |
entry |
comments |
Ectoine is an osmoprotectant that is found in halophilic eubacteria. This is the third enzyme in the ectoine-biosynthesis pathway, the other enzymes involved being EC 2.6.1.76, diaminobutyrate—2-oxoglutarate transaminase and EC 2.3.1.177, diaminobutyrate acetyltransferase [1,2]. |
Ectoine is an osmoprotectant that is found in halophilic eubacteria. This is the third enzyme in the ectoine-biosynthesis pathway, the other enzymes involved being EC 2.6.1.76, diaminobutyrate—2-oxoglutarate transaminase and EC 2.3.1.178, diaminobutyrate acetyltransferase [1,2]. |
| 1205 |
2005-12-12 07:14:23 |
4.2.1.108 |
entry |
comments |
Ectoine is an osmoprotectant that is found in halophilic eubacteria. This is the third enzyme in the ectoine-biosynthesis pathway, the other enzymes involved being EC 2.6.1.76, diaminobutyrate—2-oxoglutarate transaminase and EC 2.3.1.178, diaminobutyrate acetyltransferase [1,2]. |
Ectoine is an osmoprotectant that is found in halophilic eubacteria. This is the third enzyme in the ectoine-biosynthesis pathway, the other enzymes involved being EC 2.6.1.76, diaminobutyrate---2-oxoglutarate transaminase and EC 2.3.1.178, diaminobutyrate acetyltransferase [1,2]. |
| 1223 |
2005-12-12 07:55:55 |
2.3.1.179 |
entry |
cas_num |
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|
| 1222 |
2005-12-12 07:55:55 |
2.3.1.179 |
entry |
diagram |
|
|
| 1220 |
2005-12-12 07:55:55 |
2.3.1.179 |
entry |
serial |
|
179 |
| 1219 |
2005-12-12 07:55:55 |
2.3.1.179 |
entry |
subsubclass |
|
1 |
| 1218 |
2005-12-12 07:55:55 |
2.3.1.179 |
entry |
subclass |
|
3 |
| 1217 |
2005-12-12 07:55:55 |
2.3.1.179 |
entry |
class |
|
2 |
| 1216 |
2005-12-12 07:55:55 |
2.3.1.179 |
entry |
links |
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|
| 1215 |
2005-12-12 07:55:55 |
2.3.1.179 |
entry |
comments |
|
Involved in the dissociated (or type II) fatty acid biosynthesis system that occurs in plants and bacteria. While the substrate specificity of this enzyme is very similar to that of EC 2.3.1.41, beta-ketoacyl-ACP synthase I, it differs in that palmitoleoyl-ACP is not a good substrate of EC 2.3.1.41 but is an excellent substrate of this enzyme [1,2]. The fatty acid composition of Escherichia coli changes as a function of growth temperature, with the proportion of unsaturated fatty acids increasing with lower growth temperature. This enzyme controls the temperature-dependent regulation of fatty acid composition, with mutants lacking this acivity being deficient in the elongation of palmitoleate to cis-vaccenate at low temperatures [3,4]. |
| 1214 |
2005-12-12 07:55:55 |
2.3.1.179 |
entry |
sys_name |
|
palmitoleoyl-[acyl-carrier protein]:malonyl-[acyl-carrier protein] C-acyltransferase (decarboxylating) |
| 1233 |
2005-12-12 07:55:55 |
2.3.1.179 |
entry |
glossary |
|
|
| 1210 |
2005-12-12 07:55:55 |
2.3.1.179 |
entry |
ec_num |
|
2.3.1.179 |
