| EC |
4.2.2.15 |
| Accepted name: |
anhydrosialidase |
| Reaction: |
Elimination of α-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-α-N-acetylneuraminate |
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For diagram of reaction, click here |
| Other name(s): |
anhydroneuraminidase; sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing); sialidase L |
| Systematic name: |
glycoconjugate sialyl-lyase (2,7-cyclizing) |
| Comments: |
Also acts on N-glycolylneuraminate glycosides. cf. EC 3.2.1.18 (exo-α-sialidase) and EC 3.2.1.129 (endo-α-sialidase). |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 157857-11-9 |
| References: |
| 1. |
Li, Y.-T., Nakagawa, H., Ross, S.A., Hansson, G.C. and Li, S.C. A novel sialidase which releases 2,7-anhydro-α-N-acetylneuraminic acid from sialoglycoconjugates. J. Biol. Chem. 265 (1990) 21629–21633. [PMID: 2254319] |
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| [EC 4.2.2.15 created 1992 as EC 3.2.1.138, transferred 2003 to EC 4.2.2.15] |
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