| EC |
3.2.1.18 |
| Accepted name: |
exo-α-sialidase |
| Reaction: |
Hydrolysis of α-(2→3)-, α-(2→6)-, α-(2→8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates |
| Other name(s): |
neuraminidase; sialidase; α-neuraminidase; acetylneuraminidase |
| Systematic name: |
acetylneuraminyl hydrolase |
| Comments: |
The enzyme does not act on 4-O-acetylated sialic acids. endo-α-Sialidase activity is listed as EC 3.2.1.129, endo-α-sialidase. See also EC 4.2.2.15 anhydrosialidase. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9001-67-6 |
| References: |
| 1. |
Schauer, R. Sialic acids. Adv. Carbohydr. Chem. Biochem. 40 (1982) 131–234. [DOI] [PMID: 6762816] |
| 2. |
Cabezas, J.A. Some questions and suggestions on the type references of the official nomenclature (IUB) for sialidase(s) and endosialidase. Biochem. J. 278 (1991) 311–312. [PMID: 1883340] |
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| [EC 3.2.1.18 created 1961, modified 1999] |
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