The Enzyme Database

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EC 6.4.1.9     
Accepted name: coenzyme F430 synthetase
Reaction: ATP + 15,173-seco-F430-173-acid = ADP + phosphate + coenzyme F430
Other name(s): cfbE (gene name)
Systematic name: 15,173-seco-F430-173-acid cyclo-ligase (ADP-forming)
Comments: The enzyme, studied from the methanogenic archaeon Methanosarcina acetivorans, catalyses the last step in the biosynthesis of the nickel-containing tetrapyrrole cofactor coenzyme F430, which is required by EC 2.8.4.1, coenzyme-B sulfoethylthiotransferase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Zheng, K., Ngo, P.D., Owens, V.L., Yang, X.P. and Mansoorabadi, S.O. The biosynthetic pathway of coenzyme F430 in methanogenic and methanotrophic archaea. Science 354 (2016) 339–342. [PMID: 27846569]
[EC 6.4.1.9 created 2017]
 
 


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