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Your query returned 1 entry. Printable version
EC | 2.8.4.1 | ||||||||||
Accepted name: | coenzyme-B sulfoethylthiotransferase | ||||||||||
Reaction: | methyl-CoM + CoB = CoM-S-S-CoB + methane | ||||||||||
For diagram of methane biosynthesis, click here | |||||||||||
Glossary: | CoB = coenzyme B = N-(7-sulfanylheptanoyl)threonine = N-(7-mercaptoheptanoyl)threonine 3-O-phosphate (deprecated) CoM = coenzyme M = 2-sulfanylethane-1-sulfonate = 2-mercaptoethanesulfonate (deprecated) |
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Other name(s): | methyl-CoM reductase; methyl coenzyme M reductase | ||||||||||
Systematic name: | methyl-CoM:CoB S-(2-sulfoethyl)thiotransferase | ||||||||||
Comments: | This enzyme catalyses the final step in methanogenesis, the biological production of methane. This important anaerobic process is carried out only by methanogenic archaea. The enzyme can also function in reverse, for anaerobic oxidation of methane.The enzyme requires the hydroporphinoid nickel complex coenzyme F430. Highly specific for coenzyme B with a heptanoyl chain; ethyl CoM and difluoromethyl CoM are poor substrates. The sulfide sulfur can be replaced by selenium but not by oxygen. | ||||||||||
Links to other databases: | BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB | ||||||||||
References: |
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