The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 3.8.1.6     
Accepted name: 4-chlorobenzoate dehalogenase
Reaction: 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride
Other name(s): halobenzoate dehalogenase
Systematic name: 4-chlorobenzoate chlorohydrolase
Comments: Catalyses the first step in the degradation of chlorobenzoate in Pseudomonas. In many microorganisms, this activity comprises three separate enzymes, EC 6.2.1.33 (4-chlorobenzoate—CoA ligase), EC 3.8.1.7 (4-chlorobenzoyl-CoA dehalogenase) and EC 3.1.2.23 (4-hydroxybenzoyl-CoA thioesterase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 94047-11-7
References:
1.  Müller, R., Thiele, J., Klages, U. and Lingens, F. Incorporation of [18O]water into 4-hydroxybenzoic acid in the reaction of 4-chlorobenzoate dehalogenase from Pseudomonas spec. CBS 3. Biochem. Biophys. Res. Commun. 124 (1984) 178–182. [PMID: 6497878]
2.  Heppel, L.A. and Porterfield, V.T. Enzymatic dehalogenation of certain brominated and chlorinated compounds. J. Biol. Chem. 176 (1948) 763–769. [PMID: 18889931]
[EC 3.8.1.6 created 1989, modified 1999]
 
 


Data © 2001–2016 IUBMB
Web site © 2005–2016 Andrew McDonald