4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride
4-chlorobenzoyl CoA chlorohydrolase
Specific for dehalogenation at the 4-position. Can dehalogenate substrates bearing fluorine, chlorine, bromine and iodine in the 4-position. This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway.
Chang, K.H., Liang, P.H., Beck, W., Scholten, J.D., Dunaway-Mariano, D. Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3. Biochemistry31 (1992) 5605–5610. [PMID: 1610806]
Crooks, G.P., Copley, S.D. Purification and characterization of 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain 4-CB1. Biochemistry,33 (1994) 11645–11649. [PMID: 7918379]