The Enzyme Database

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EC 3.5.3.12     
Accepted name: agmatine deiminase
Reaction: agmatine + H2O = N-carbamoylputrescine + NH3
Glossary: agmatine = (4-aminobutyl)guanidine
Other name(s): agmatine amidinohydrolase
Systematic name: agmatine iminohydrolase
Comments: The plant enzyme also catalyses the reactions of EC 2.1.3.3 (ornithine carbamoyltransferase), EC 2.1.3.6 (putrescine carbamoyltransferase) and EC 2.7.2.2 (carbamate kinase), thus functioning as a putrescine synthase, converting agmatine and ornithine into putrescine and citrulline, respectively.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37289-17-1
References:
1.  Smith, T.A. Agmatine iminohydrolase in maize. Phytochemistry 8 (1969) 2111–2117.
2.  Srivenugopal, K.S. and Adiga, P.R. Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and properties of a multifunctional enzyme (putrescine synthase). J. Biol. Chem. 256 (1981) 9532–9541. [PMID: 6895223]
[EC 3.5.3.12 created 1972]
 
 


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