The Enzyme Database

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Accepted name: 3-oxo-5,6-didehydrosuberyl-CoA thiolase
Reaction: 2,3-didehydroadipoyl-CoA + acetyl-CoA = CoA + 3-oxo-5,6-didehydrosuberoyl-CoA
Glossary: 2,3-didehydroadipoyl-CoA = 5-carboxypent-2-enoyl-CoA
3-oxo-5,6-didehydrosuberoyl-CoA = 7-carboxy-3-oxohept-5-enoyl-CoA
Other name(s): paaJ (gene name)
Systematic name: 2,3-didehydroadipoyl-CoA:acetyl-CoA C-didehydroadipoyltransferase (double bond migration)
Comments: The enzyme acts in the opposite direction. The enzymes from the bacteria Escherichia coli and Pseudomonas sp. Y2 also have the activity of EC (3-oxoadipyl-CoA thiolase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Teufel, R., Mascaraque, V., Ismail, W., Voss, M., Perera, J., Eisenreich, W., Haehnel, W. and Fuchs, G. Bacterial phenylalanine and phenylacetate catabolic pathway revealed. Proc. Natl. Acad. Sci. USA 107 (2010) 14390–14395. [PMID: 20660314]
[EC created 2013]

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