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Your query returned 4 entries. Printable version
EC | 1.3.8.4 | ||||||||||
Accepted name: | isovaleryl-CoA dehydrogenase | ||||||||||
Reaction: | isovaleryl-CoA + electron-transfer flavoprotein = 3-methylcrotonyl-CoA + reduced electron-transfer flavoprotein | ||||||||||
Other name(s): | isovaleryl-coenzyme A dehydrogenase; isovaleroyl-coenzyme A dehydrogenase; 3-methylbutanoyl-CoA:(acceptor) oxidoreductase | ||||||||||
Systematic name: | 3-methylbutanoyl-CoA:electron-transfer flavoprotein oxidoreductase | ||||||||||
Comments: | Contains a tightly-bound FAD cofactor. Pentanoate can act as donor. | ||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37274-61-6 | ||||||||||
References: |
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EC | 1.3.99.10 | ||||||||||
Transferred entry: | isovaleryl-CoA dehydrogenase. Now EC 1.3.8.4, isovaleryl-CoA dehydrogenase | ||||||||||
EC | 2.3.1.93 | ||||||||||
Accepted name: | 13-hydroxylupanine O-tigloyltransferase | ||||||||||
Reaction: | (E)-2-methylcrotonoyl-CoA + 13-hydroxylupanine = CoA + 13-[(E)-2-methylcrotonoyl]oxylupanine | ||||||||||
Glossary: | (E)-2-methylcrotonoyl-CoA = tigloyl-CoA = (E)-2-methylbut-2-enoyl-CoA | ||||||||||
Other name(s): | tigloyl-CoA:13-hydroxylupanine O-tigloyltransferase; 13-hydroxylupanine acyltransferase | ||||||||||
Systematic name: | (E)-2-methylcrotonoyl-CoA:13-hydroxylupanine O-2-methylcrotonoyltransferase | ||||||||||
Comments: | Benzoyl-CoA and, more slowly, pentanoyl-CoA, 3-methylbutanoyl-CoA and butanoyl-CoA can act as acyl donors. Involved in the synthesis of lupanine alkaloids. | ||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 85341-00-0 | ||||||||||
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EC | 2.3.1.300 | ||||||||||
Accepted name: | branched-chain β-ketoacyl-[acyl-carrier-protein] synthase | ||||||||||
Reaction: | (1) 3-methylbutanoyl-CoA + a malonyl-[acyl-carrier protein] = a 5-methyl-3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2 (2) 2-methylpropanoyl-CoA + a malonyl-[acyl-carrier protein] = a 4-methyl-3-oxopentanoyl-[acyl-carrier-protein] + CoA + CO2 (3) (2S)-2-methylbutanoyl-CoA + a malonyl-[acyl-carrier protein] = a (4S)-4-methyl-3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2 |
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Glossary: | 3-methylbutanoyl-CoA = isovaleryl-CoA 2-methylpropanoyl-CoA = isobutanoyl-CoA = isobutyryl-CoA |
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Systematic name: | 3-methylbutanoyl-CoA:malonyl-[acyl-carrier protein] C-acyltransferase | ||||||||||
Comments: | The enzyme is responsible for initiating branched-chain fatty acid biosynthesis by the dissociated (or type II) fatty-acid biosynthesis system (FAS-II) in some bacteria, using molecules derived from degradation of the branched-chain amino acids L-leucine, L-valine, and L-isoleucine to form the starting molecules for elongation by the FAS-II system. In some organisms the enzyme is also able to use acetyl-CoA, leading to production of a mix of branched-chain and straight-chain fatty acids [3] (cf. EC 2.3.1.180, β-ketoacyl-[acyl-carrier-protein] synthase III). | ||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||
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