| EC |
3.4.21.55 |
| Accepted name: |
venombin AB |
| Reaction: |
Selective cleavage at Arg┼ bonds in fibrinogen to form fibrin and release fibrinopeptides A and B |
| Other name(s): |
gabonase; okinaxobin II; Bitis gabonica venom serine proteinase; afaâcytin |
| Comments: |
From the venom of the Gaboon viper Bitis gabonica. Activates Factor XIII. Not inhibited by antithrombin III/heparin or hirudin, unlike EC 3.4.21.5, thrombin |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 104003-74-9 |
| References: |
| 1. |
Pirkle, H., Theodor, I., Miyada, D. and Simmons, G. Thrombin-like enzyme from the venom of Bitis gabonica. Purification, properties and coagulant actions. J. Biol. Chem. 261 (1986) 8830–8835. [PMID: 3522580] |
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| [EC 3.4.21.55 created 1989] |
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