EC |
3.1.2.5 |
Accepted name: |
hydroxymethylglutaryl-CoA hydrolase |
Reaction: |
(S)-3-hydroxy-3-methylglutaryl-CoA + H2O = CoA + 3-hydroxy-3-methylglutarate |
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For diagram of the mevalonate-biosynthesis pathway, click here |
Other name(s): |
β-hydroxy-β-methylglutaryl coenzyme A hydrolase; β-hydroxy-β-methylglutaryl coenzyme A deacylase; hydroxymethylglutaryl coenzyme A hydrolase; hydroxymethylglutaryl coenzyme A deacylase; 3-hydroxy-3-methylglutaryl-CoA hydrolase |
Systematic name: |
(S)-3-hydroxy-3-methylglutaryl-CoA hydrolase |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 9025-89-2 |
References: |
1. |
Dekker, E.E., Schlesinger, M.J. and Coon, M.J. β-Hydroxy-β-methylglutaryl coenzyme A deacetylase. J. Biol. Chem. 233 (1958) 434–438. [PMID: 13563516] |
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[EC 3.1.2.5 created 1961] |
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