| EC |
3.1.2.16 |
| Accepted name: |
citrate-lyase deacetylase |
| Reaction: |
acetyl-[citrate (pro-3S)-lyase] + H2O = holo-[citrate (pro-3S)-lyase] + acetate |
| Other name(s): |
[citrate-(pro-3S)-lyase] thiolesterase; acetyl-S-(acyl-carrier protein) enzyme thioester hydrolase; citrate lyase deacetylase; [citrate-(pro-3S)-lyase](acetyl-form) hydrolase |
| Systematic name: |
acetyl-[citrate-(pro-3S)-lyase] hydrolase |
| Comments: |
In the proteobacterium Rubrivivax gelatinosus, this enzyme modulates the activity of EC 4.1.3.6, citrate (pro-3S)-lyase, by converting it from its active acetyl form into its inactive thiol form by removal of its acetyl groups [2]. The activity of citrate-lyase deacetylase is itself inhibited by L-glutamate [2]. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 58319-93-0 |
| References: |
| 1. |
Giffhorn, F. and Gottschalk, G. Inactivation of citrate lyase from Rhodopseudomonas gelatinosa by a specific deacetylase and inhibition of this inactivation by L-(+)-glutamate. J. Bacteriol. 124 (1975) 1052–1061. [PMID: 356] |
| 2. |
Giffhorn, F., Rode, H., Kuhn, A. and Gottschalk, G. Citrate lyase deacetylase of Rhodopseudomonas gelatinosa. Isolation of the enzyme and studies on the inhibition by L-glutamate. Eur. J. Biochem. 111 (1980) 461–471. [DOI] [PMID: 7460909] |
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| [EC 3.1.2.16 created 1989] |
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