| EC |
2.6.1.37 |
| Accepted name: |
2-aminoethylphosphonate—pyruvate transaminase |
| Reaction: |
(2-aminoethyl)phosphonate + pyruvate = 2-phosphonoacetaldehyde + L-alanine |
| Other name(s): |
(2-aminoethyl)phosphonate transaminase; (2-aminoethyl)phosphonate aminotransferase; (2-aminoethyl)phosphonic acid aminotransferase; 2-aminoethylphosphonate-pyruvate aminotransferase; 2-aminoethylphosphonate aminotransferase; 2-aminoethylphosphonate transaminase; AEP transaminase; AEPT |
| Systematic name: |
(2-aminoethyl)phosphonate:pyruvate aminotransferase |
| Comments: |
A pyridoxal-phosphate protein. 2-Aminoethylarsonate can replace 2-aminoethylphosphonate as a substrate. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37277-91-1 |
| References: |
| 1. |
La Nauze, J.M. and Rosenberg, H. The identification of 2-phosphonoacetaldehyde as an intermediate in the degradation of 2-aminoethylphosphonate by Bacillus cereus. Biochim. Biophys. Acta 165 (1968) 438–447. [DOI] [PMID: 4982500] |
| 2. |
Dumora, C., Lacoste, A.-M. and Cassaigne, A. Purification and properties of 2-aminoethylphosphonate:pyruvate aminotransferase from Pseudomonas aeruginosa. Eur. J. Biochem. 133 (1983) 119–125. [DOI] [PMID: 6406228] |
| 3. |
Lacoste, A.-M., Dumora, C., Balas, L., Hammerschmidt, F. and Vercauteren, J. Stereochemistry of the reaction catalysed by 2-aminoethylphosphonate aminotransferase. A 1H-NMR study. Eur. J. Biochem. 215 (1993) 841–844. [DOI] [PMID: 8394813] |
| 4. |
Lacoste, A.-M., Dumora, C., Ali, B.R.S., Neuzil, E. and Dixon, H.B.F. Utilization of 2-aminoethylarsonic acid in Pseudomonas aeruginosa. J. Gen. Microbiol. 138 (1992) 1283–1287. [DOI] [PMID: 1527499] |
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| [EC 2.6.1.37 created 1972, modified 1982, modified 2001] |
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