ExplorEnz: EC 2.5.1.100

Your query returned 1 entry. Printable version

2.5.1.100

Accepted name:

fumigaclavine A dimethylallyltransferase

Reaction:

fumigaclavine A + prenyl diphosphate = fumigaclavine C + diphosphate

For diagram of fumigaclavin alkaloid biosynthesis, click here

Glossary:

fumigaclavine A = 6,8β-dimethylergolin-9β-yl acetate;
fumigaclavine C = 6,8β-dimethyl-2-(2-methylbut-3-en-2-yl)ergolin-9β-yl acetate

Other name(s):

FgaPT1; dimethylallyl-diphosphate:fumigaclavine A dimethylallyltransferase

Systematic name:

prenyl-diphosphate:fumigaclavine A prenyltransferase

Comments:

Fumigaclavine C is an ergot alkaloid produced by some fungi of the Trichocomaceae family. Activity does not require any metal ions.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Unsöld, I.A. and Li, S.M. Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1. ChemBioChem 7 (2006) 158–164. [DOI] [PMID: 16397874]

[EC 2.5.1.100 created 2012]