| EC |
2.5.1.100 |
| Accepted name: |
fumigaclavine A dimethylallyltransferase |
| Reaction: |
fumigaclavine A + prenyl diphosphate = fumigaclavine C + diphosphate |
| Glossary: |
fumigaclavine A = 6,8β-dimethylergolin-9β-yl acetate;
fumigaclavine C = 6,8β-dimethyl-2-(2-methylbut-3-en-2-yl)ergolin-9β-yl acetate |
| Other name(s): |
FgaPT1; dimethylallyl-diphosphate:fumigaclavine A dimethylallyltransferase |
| Systematic name: |
prenyl-diphosphate:fumigaclavine A prenyltransferase |
| Comments: |
Fumigaclavine C is an ergot alkaloid produced by some fungi of the Trichocomaceae family. Activity does not require any metal ions. |
| References: |
| 1. |
Unsöld, I.A. and Li, S.M. Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1. ChemBioChem 7 (2006) 158–164. [PMID: 16397874] |
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| [EC 2.5.1.100 created 2012] |
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