| EC |
1.5.1.6 |
| Accepted name: |
formyltetrahydrofolate dehydrogenase |
| Reaction: |
10-formyltetrahydrofolate + NADP+ + H2O = tetrahydrofolate + CO2 + NADPH + H+ |
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For diagram of folate cofactors, click here and for diagram of C1 metabolism, click here |
| Other name(s): |
10-formyl tetrahydrofolate:NADP oxidoreductase; 10-formyl-H2PtGlu:NADP oxidoreductase; 10-formyl-H4folate dehydrogenase; N10-formyltetrahydrofolate dehydrogenase; 10-formyltetrahydrofolate dehydrogenase |
| Systematic name: |
10-formyltetrahydrofolate:NADP+ oxidoreductase |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37256-25-0 |
| References: |
| 1. |
Kutzbach, C. and Stokstad, E.L.R. Partial purification of a 10-formyl-tetrahydrofolate: NADP oxidoreductase from mammalian liver. Biochem. Biophys. Res. Commun. 30 (1968) 111–117. [DOI] [PMID: 4384443] |
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| [EC 1.5.1.6 created 1972] |
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