C1 Metabolism

Folate Coenzymes

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Only the part of the formula within the dotted lines is shown in the diagram below.

© IUBMB 2003


1. For folate names and symbols click here

2. For the biosynthesis of dihydrofolate, click here.

3. The dissociation constant for the reaction
          5,10-CH2-H4folate = H4folate + CH2O
     is about 30 μM.

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enzymes homepage.
histidine catabolism
purine biosynthesis
EC methylenetetrahydrofolate dehydrogenase (NADP+)
EC formyltetrahydrofolate dehydrogenase
EC methylenetetrahydrofolate reductase (NADPH)
EC 5-methyltetrahydrofolate-homocysteine S-methyltransferase (mechanism)
EC thymidylate synthase
EC thymidylate synthase (FAD)
EC glutamate formiminotransferase
EC methionyl-tRNA formyltransferase
EC methenyltetrahydrofolate cyclohydrolase
EC formiminotetrahydrofolate cyclodeaminase
EC 5-formyltetrahydrofolate cyclo-ligase
EC formate-tetrahydrofolate ligase