| EC |
1.5.1.45 |
| Accepted name: |
FAD reductase [NAD(P)H] |
| Reaction: |
FADH2 + NAD(P)+ = FAD + NAD(P)H + H+ |
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For diagram of FAD biosynthesis, click here |
| Other name(s): |
GTNG_3158 (gene name) |
| Systematic name: |
FADH2:NAD(P)+ oxidoreductase |
| Comments: |
This enzyme, isolated from the bacterium Geobacillus thermodenitrificans, participates in the pathway of tryptophan degradation. The enzyme is part of a system that also includes a bifunctional riboflavin kinase/FMN adenylyltransferase and EC 1.14.14.8, anthranilate 3-monooxygenase (FAD). It can reduce either FAD or flavin mononucleotide (FMN) but prefers FAD. The enzyme has a slight preference for NADPH as acceptor. cf. EC 1.5.1.37, FAD reductase (NADH). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Liu, X., Dong, Y., Li, X., Ren, Y., Li, Y., Wang, W., Wang, L. and Feng, L. Characterization of the anthranilate degradation pathway in Geobacillus thermodenitrificans NG80-2. Microbiology 156 (2010) 589–595. [DOI] [PMID: 19942660] |
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| [EC 1.5.1.45 created 2012] |
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