| EC |
1.2.1.89 |
| Accepted name: |
D-glyceraldehyde dehydrogenase (NADP+) |
| Reaction: |
D-glyceraldehyde + NADP+ + H2O = D-glycerate + NADPH + H+ |
| Other name(s): |
glyceraldehyde dehydrogenase; GADH |
| Systematic name: |
D-glyceraldehyde:NADP+ oxidoreductase |
| Comments: |
The enzyme from the archaea Thermoplasma acidophilum and Picrophilus torridus is involved in the non-phosphorylative Entner-Doudoroff pathway. cf. EC 1.2.99.8, glyceraldehyde dehydrogenase (FAD-containing). |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Jung, J.H. and Lee, S.B. Identification and characterization of Thermoplasma acidophilum glyceraldehyde dehydrogenase: a new class of NADP+-specific aldehyde dehydrogenase. Biochem. J. 397 (2006) 131–138. [DOI] [PMID: 16566751] |
| 2. |
Reher, M. and Schonheit, P. Glyceraldehyde dehydrogenases from the thermoacidophilic euryarchaeota Picrophilus torridus and Thermoplasma acidophilum, key enzymes of the non-phosphorylative Entner-Doudoroff pathway, constitute a novel enzyme family within the aldehyde dehydrogenase superfamily. FEBS Lett. 580 (2006) 1198–1204. [DOI] [PMID: 16458304] |
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| [EC 1.2.1.89 created 2014] |
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