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Your query returned 1 entry. Printable version
EC | 1.14.13.179 | ||||
Accepted name: | methylxanthine N3-demethylase | ||||
Reaction: | (1) theobromine + O2 + NAD(P)H + H+ = 7-methylxanthine + NAD(P)+ + H2O + formaldehyde (2) 3-methylxanthine + O2 + NAD(P)H + H+ = xanthine + NAD(P)+ + H2O + formaldehyde |
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Glossary: | theobromine = 3,7-dimethylxanthine |
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Other name(s): | ndmB (gene name) | ||||
Systematic name: | theobromine:oxygen oxidoreductase (N3-demethylating) | ||||
Comments: | A non-heme iron oxygenase. The enzyme from the bacterium Pseudomonas putida shares an NAD(P)H-FMN reductase subunit with EC 1.14.13.178, methylxanthine N1-demethylase, and has higher activity with NADH than with NADPH [1]. Also demethylates caffeine and theophylline with lower efficiency. Forms part of the degradation pathway of methylxanthines. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||
References: |
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