| EC |
5.4.3.9 |
| Accepted name: |
glutamate 2,3-aminomutase |
| Reaction: |
L-glutamate = 3-aminopentanedioate |
| Glossary: |
3-aminopentanedioate = isoglutamate |
| Systematic name: |
L-glutamate 2,3-aminomutase |
| Comments: |
This enzyme is a member of the ’AdoMet radical’ (radical SAM) family. It contains pyridoxal phosphate and a [4Fe-4S] cluster, which is coordinated by 3 cysteines and binds an exchangeable S-adenosyl-L-methionine molecule. During the reaction cycle, the AdoMet forms a 5′-deoxyadenosyl radical, which is regenerated at the end of the reaction. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc |
| References: |
| 1. |
Ruzicka, F.J. and Frey, P.A. Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes. Biochim. Biophys. Acta 1774 (2007) 286–296. [DOI] [PMID: 17222594] |
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| [EC 5.4.3.9 created 2012] |
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