The Enzyme Database

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EC 5.4.3.9     
Accepted name: glutamate 2,3-aminomutase
Reaction: L-glutamate = 3-aminopentanedioate
Glossary: 3-aminopentanedioate = isoglutamate
Systematic name: L-glutamate 2,3-aminomutase
Comments: This enzyme is a member of the ’AdoMet radical’ (radical SAM) family. It contains pyridoxal phosphate and a [4Fe-4S] cluster, which is coordinated by 3 cysteines and binds an exchangeable S-adenosyl-L-methionine molecule. During the reaction cycle, the AdoMet forms a 5′-deoxyadenosyl radical, which is regenerated at the end of the reaction.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Ruzicka, F.J. and Frey, P.A. Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes. Biochim. Biophys. Acta 1774 (2007) 286–296. [PMID: 17222594]
[EC 5.4.3.9 created 2012]
 
 


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