| EC |
5.3.3.8 |
| Accepted name: |
dodecenoyl-CoA isomerase |
| Reaction: |
(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA |
| Other name(s): |
dodecenoyl-CoA Δ-isomerase; Δ3-cis-Δ2-trans-enoyl-CoA isomerase; acetylene-allene isomerase; dodecenoyl-CoA Δ-isomerase; dodecenoyl-CoA Δ3-cis-Δ2-trans-isomerase |
| Systematic name: |
dodecenoyl-CoA (3Z)-(2E)-isomerase |
| Comments: |
Also catalyses the interconversion of 3-acetylenic fatty acyl thioesters and (+)-2,3-dienoyl fatty acyl thioesters, with fatty acid chain lengths C6 to C12. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, METACYC, PDB, CAS registry number: 62213-29-0 |
| References: |
| 1. |
Miesowicz, F.M. and Bloch, K. Purification of hog liver isomerase. Mechanism of isomerization of 3-alkenyl and 3-alkynyl thioesters. J. Biol. Chem. 254 (1979) 5868–5877. [PMID: 376522] |
| 2. |
Stoffel, W., Ditzer, R. and Caesar, H. Der Stoffwechsel der ungesättigten Fettsäuren. III. Zur β-Oxydation der Mono- und Polyenfettsäuren. Der Mechanismus der enzymatischen Reaktionen an Δ3cis-Enoyl-CoA-Verbindungen. Hoppe-Seyler's Z. Physiol. Chem. 339 (1964) 167–181. [PMID: 5830064] |
| 3. |
Stoffel, W. and Ecker, W. Δ3-cis,-Δ2-trans-Enoyl-CoA isomerase from rat liver mitochondria. Methods Enzymol. 14 (1979) 99–105. |
| 4. |
Stoffel, W. and Grol, M. Purification and properties of 3-cis-2-trans-enoyl-CoA isomerase (dodecenoyl-CoA Δ-isomerase) from rat liver mitochondria. Hoppe-Seyler's Z. Physiol. Chem. 359 (1978) 1777–1782. [PMID: 738702] |
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| [EC 5.3.3.8 created 1978, modified 1980] |
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