The Enzyme Database

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EC 5.3.1.8     
Accepted name: mannose-6-phosphate isomerase
Reaction: D-mannose 6-phosphate = D-fructose 6-phosphate
For diagram of GDP-L-fucose and GDP-mannose biosynthesis, click here
Other name(s): phosphomannose isomerase; phosphohexomutase; phosphohexoisomerase; mannose phosphate isomerase; phosphomannoisomerase; D-mannose-6-phosphate ketol-isomerase
Systematic name: D-mannose-6-phosphate aldose-ketose-isomerase
Comments: A zinc protein.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9023-88-5
References:
1.  Bruns, F.H., Noltmann, E. and Willemsen, A. Phosphomannose-isomerase. I. Über die Aktivitätsmessung und die Sulfhydryl-sowie die metallabhängigkeit der Enzymirkung in einigen Tierischen Geweben. Biochem. Z. 330 (1958) 411–420. [PMID: 13596383]
2.  Gracy, R.W. and Noltmann, E.A. Studies on phosphomannose isomerase. II. Characterization as a zinc metalloenzyme. J. Biol. Chem. 243 (1968) 4109–4116. [PMID: 4969968]
3.  Slein, M.W. Phosphomannose isomerase. J. Biol. Chem. 186 (1950) 753–761. [PMID: 14794671]
[EC 5.3.1.8 created 1961, modified 1976]
 
 


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