EC |
4.2.3.225 |
Accepted name: |
cattleyene synthase |
Reaction: |
geranylgeranyl diphosphate = cattleyene + diphosphate |
Glossary: |
cattleyene = (3R,3aS,5aS,5bR,8aR)-3,3a,6,6,8a-pentamethyl-2,3,3a,4,5,5a,5b,6,7,8,8a,9-dodecahydro-1H-pentaleno[2,1-e]indene |
Other name(s): |
CyS |
Systematic name: |
geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, cattleyene-formimg) |
Comments: |
A diterpene synthase isolated from the bacterium Streptantibioticus cattleyicolor. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Rinkel, J., Steiner, S.T. and Dickschat, J.S. Diterpene biosynthesis in actinomycetes: studies on cattleyene synthase and phomopsene synthase. Angew. Chem. Int. Ed. Engl. 58 (2019) 9230–9233. [DOI] [PMID: 31034729] |
2. |
Xing, B., Xu, H., Li, A., Lou, T., Xu, M., Wang, K., Xu, Z., Dickschat, J.S., Yang, D. and Ma, M. Crystal structure based mutagenesis of cattleyene synthase leads to the generation of rearranged polycyclic diterpenes. Angew. Chem. Int. Ed. Engl. 61:e202209785 (2022). [DOI] [PMID: 35819825] |
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[EC 4.2.3.225 created 2024] |
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