EC |
4.2.3.217 |
Accepted name: |
somaliensene B synthase |
Reaction: |
geranylfarnesyl diphosphate = (–)-somaliensene B + diphosphate |
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For diagram of somaliensene A and B biosynthesis, click here |
Glossary: |
(–)-somaliensene B = (4S)-1-methyl-4-[(5E,9E,13E)-6,10,14-trimethylpentadeca-1,5,9,13-tetraen-2-yl]cyclohex-1-ene |
Other name(s): |
stsC (gene name) |
Systematic name: |
geranylfarnesyl-diphosphate diphosphate-lyase (cyclizing, (–)-somaliensene B-forming) |
Comments: |
A sesterterpenoid synthase enzyme isolated from the bacterium Streptomyces somaliensis. The enzyme also produces somaliensene A (cf. EC 4.2.3.216, somaliensene A synthase). |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Yang, Y., Zhang, Y., Zhang, S., Chen, Q., Ma, K., Bao, L., Tao, Y., Yin, W., Wang, G. and Liu, H. Identification and characterization of a membrane-bound sesterterpene cyclase from Streptomyces somaliensis. J Nat Prod 81 (2018) 1089–1092. [DOI] [PMID: 29553734] |
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[EC 4.2.3.217 created 2023] |
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