The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: sabinene-hydrate synthase
Reaction: geranyl diphosphate + H2O = sabinene hydrate + diphosphate
For diagram of monoterpenoid biosynthesis, click here
Other name(s): sabinene hydrate cyclase
Systematic name: geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming)
Comments: Both cis- and trans- isomers of sabinene hydrate are formed. (3R)-Linalyl diphosphate is an intermediate in the reaction
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 117164-95-1
1.  Hallahan, T.W. and Croteau, R. Monoterpene biosynthesis: demonstration of a geranyl pyrophosphate:sabinene hydrate cyclase in soluble enzyme preparations from sweet marjoram (Majorana hortensis). Arch. Biochem. Biophys. 264 (1988) 618–631. [PMID: 3401015]
2.  Hallahan, T.W. and Croteau, R. Monoterpene biosynthesis: mechanism and stereochemistry of the enzymatic cyclization of geranyl pyrophosphate to (+)-cis- and (+)-trans-sabinene hydrate. Arch. Biochem. Biophys. 269 (1989) 313–326. [PMID: 2916845]
[EC created 1992 as EC, transferred 2000 to EC]

Data © 2001–2016 IUBMB
Web site © 2005–2016 Andrew McDonald