The Enzyme Database

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EC 4.1.3.14     
Accepted name: L-erythro-3-hydroxyaspartate aldolase
Reaction: L-erythro-3-hydroxy-aspartate = glycine + glyoxylate
Other name(s): L-erythro-β-hydroxyaspartate aldolase; L-erythro-β-hydroxyaspartate glycine-lyase; erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase
Systematic name: L-erythro-3-hydroxy-aspartate glyoxylate-lyase (glycine-forming)
Comments: A pyridoxal-phosphate protein. The enzyme, purified from the bacterium Paracoccus denitrificans NCIMB 8944, is strictly specific for the L-erythro stereoisomer of 3-hydroxyaspartate. Different from EC 4.1.3.41, erythro-3-hydroxy-D-aspartate aldolase. Requires a divalent cation.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37290-64-5
References:
1.  Gibbs, R.G. and Morris, J.G. Assay and properties of β-hydroxyaspartate aldolase from Micrococcus denitrificans. Biochim. Biophys. Acta 85 (1964) 501–503. [PMID: 14194868]
[EC 4.1.3.14 created 1972, modified 2011]
 
 


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