The Enzyme Database

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EC 3.6.5.5     
Accepted name: dynamin GTPase
Reaction: GTP + H2O = GDP + phosphate
Systematic name: GTP phosphohydrolase (vesicle-releasing)
Comments: An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
References:
1.  Warnock, D.E. and Schmid, S.L. Dynamin GTPase, a force-generating molecular switch. Bioessays 18 (1996) 885–893. [PMID: 8939066]
2.  McClure, S.J. and Robinson, P.J. Dynamin, endocytosis and intracellular signalling. Mol. Membr. Biol. 13 (1996) 189–215. [PMID: 9116759]
3.  Oh, P., McIntosh, D.P. and Schnitzer, J.E. Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endothelium. J. Cell Biol. 141 (1998) 101–114. [PMID: 9531551]
[EC 3.6.5.5 created 2000 as EC 3.6.1.50, transferred 2003 to EC 3.6.5.5]
 
 


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