A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This is a plasma membrane enzyme, ubiquitous in animal cells, that catalyses the efflux of three Na+ and influx of two K+ per ATP hydrolysed. It is involved in generating the plasma membrane electrical potential.
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[EC 18.104.22.168 created 1984 as EC 22.214.171.124, transferred 2000 to EC 126.96.36.199, modified 2001]