The Enzyme Database

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Accepted name: 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase
Reaction: 2-(hydroxymethyl)-3-(acetamidomethylene)succinate + 2 H2O = acetate + 2-(hydroxymethyl)-4-oxobutanoate + NH3 + CO2
Other name(s): compound B hydrolase; α-hydroxymethyl-α’-(N-acetylaminomethylene)succinic acid hydrolase
Systematic name: 2-(hydroxymethyl)-3-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)
Comments: Involved in the degradation of pyridoxin by Pseudomonas and Arthrobacter.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, UM-BBD, CAS registry number: 95829-26-8
1.  Huynh, M.S. and Snell, E.E. Enzymes of vitamin B6 degradation. Purification and properties of two N-acetylamidohydrolases. J. Biol. Chem. 260 (1985) 2379–2383. [PMID: 3972793]
[EC created 1989]

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