The Enzyme Database

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EC 3.4.24.54     
Accepted name: mucrolysin
Reaction: Cleavage of Ser9┼His, His10┼Leu, Ala14┼Leu, Leu15┼Tyr and Tyr16┼Leu bonds in insulin B chain
Other name(s): Trimeresurus metalloendopeptidase A; mucrotoxin A
Comments: A 94 kDa hemorrhagic and fibrinogenolytic endopeptidase from the Chinese habu snake (Trimeresurus mucrosquamatus) venom. In peptidase family M12 (astacin family)
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 85898-38-0
References:
1.  Sugihara, H., Moriura, M. and Nikai, T. Purification and properties of a lethal, hemorrhagic protein, "mucrotoxin A", from the venom of the Chinese habu snake (Trimeresurus mucrosquamatus). Toxicon 21 (1983) 247–255. [PMID: 6857709]
2.  Kishida, M., Nikai, T., Mori, N., Kohmura, S. and Sugihara, H. Characterization of mucrotoxin A from the venom of Trimeresurus mucrosquamatus (the Chinese habu snake). Toxicon 23 (1985) 637–645. [PMID: 3904081]
[EC 3.4.24.54 created 1992]
 
 


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