The Enzyme Database

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EC 3.4.23.42     
Accepted name: thermopsin
Reaction: Similar in specificity to pepsin A preferring bulky hydrophobic amino acids in P1 and P1′
Comments: From the thermophilic archaeon Sulfolobus acidocaldarius. Maximally active at pH 2 and 90 °C. Weakly inhibited by pepstatin but shows no sequence similarity to pepsin. Type example of peptidase family A5.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 126125-05-1
References:
1.  Lin, X. and Tang, J. Thermopsin. Methods Enzymol. 248 (1995) 156–168. [PMID: 7674919]
[EC 3.4.23.42 created 1992 as EC 3.4.99.43, transferred 2000 to EC 3.4.23.42]
 
 


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