The Enzyme Database

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EC 3.4.21.49     
Accepted name: hypodermin C
Reaction: Hydrolysis of proteins including native collagen at ┼Ala bond leaving an N-terminal (75%) and a C-terminal (25%) fragment
Other name(s): Hypoderma collagenase
Comments: From the larva of a warble fly, Hypoderma lineatum. Little action on small molecule substrates of trypsin, chymotrypsin, elastase or microbial collagenases. In peptidase family S1 (trypsin family)
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 122191-36-0
References:
1.  Lecroisey, A., Boulard, C. and Keil, B. Chemical and enzymatic characterization of the collagenase from the insect Hypoderma lineatum. Eur. J. Biochem. 101 (1979) 385–393. [PMID: 230030]
2.  Lecroisey, A. and Keil, B. Specificity of the collagenase from the insect Hypoderma lineatum. Eur. J. Biochem. 152 (1985) 123–130. [PMID: 2995028]
3.  Lecroisey, A., Gilles, A.-M., De Wolf, A. and Keil, B. Complete amino acid sequence of the collagenase from the insect Hypoderma lineatum. J. Biol. Chem. 262 (1987) 7546–7551. [PMID: 3034899]
[EC 3.4.21.49 created 1981]
 
 


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