ExplorEnz: EC 3.2.1.224

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3.2.1.224

Accepted name:

D-arabinan exo β-(1,2)-arabinofuranosidase (non-reducing end)

Reaction:

Hydrolysis of terminal non-reducing β-D-arabinofuranoside residues in D-arabinans

Other name(s):

exo-β-D-arabinofuranosidase; ExoMA2

Systematic name:

β-D-arabinofuranoside non-reducing end β-D-arabinofuranosidase (configuration-retaining)

Comments:

The enzyme, characterized from the bacterium Microbacterium arabinogalactanolyticum, hydrolyses β-D-arabinofuranosides from the non-reducing terminal of D-arabinan core structure of lipoarabinomannan and arabinogalactan of mycobacterial cell wall. cf. EC 3.2.1.55, non-reducing end α-L-arabinofuranosidase; EC 3.2.1.185, non-reducing end β-L-arabinofuranosidase; EC 3.2.1.225, D-arabinan exo α-(1,3)/(1,5)-arabinofuranosidase (non-reducing end); and EC 3.2.1.226, D-arabinan endo α-(1,5)-arabinofuranosidase.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

Shimokawa, M., Ishiwata, A., Kashima, T., Nakashima, C., Li, J., Fukushima, R., Sawai, N., Nakamori, M., Tanaka, Y., Kudo, A., Morikami, S., Iwanaga, N., Akai, G., Shimizu, N., Arakawa, T., Yamada, C., Kitahara, K., Tanaka, K., Ito, Y., Fushinobu, S. and Fujita, K. Identification and characterization of endo-α-, exo-α-, and exo-β-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria. Nat. Commun. 14:5803 (2023). [DOI] [PMID: 37726269]

[EC 3.2.1.224 created 2024]