| EC |
3.1.6.9 |
| Accepted name: |
chondro-4-sulfatase |
| Reaction: |
4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-N-acetyl-D-galactosamine 4-sulfate + H2O = 4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-N-acetyl-D-galactosamine + sulfate |
| Other name(s): |
chondroitin-4-sulfatase; 4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase |
| Systematic name: |
4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase |
| Comments: |
Also acts on the saturated analogue but not on higher oligosaccharides, nor any 6-sulfates. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9045-75-4 |
| References: |
| 1. |
Held, V.E. and Buddecke, E. Nachweis, Reinigung und Eigenschaften einer Chondroitin-4-Sulfatase aus der Aorta des Rindes. Hoppe-Seyler's Z. Physiol. Chem. 348 (1967) 1047–1060. [PMID: 5595107] |
| 2. |
Roy, A.B. Sulphatases, lysosomes and disease. Aust. J. Exp. Biol. Med. Sci. 54 (1976) 111–135. [PMID: 13772] |
| 3. |
Yamagata, T., Saito, H., Habuchi, O. and Suzuki, S. Purification and properties of bacterial chondroitinases and chondrosulfatases. J. Biol. Chem. 243 (1968) 1523–1535. [PMID: 5647268] |
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| [EC 3.1.6.9 created 1972] |
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