| EC |
3.1.2.32 |
| Accepted name: |
2-aminobenzoylacetyl-CoA thioesterase |
| Reaction: |
(2-aminobenzoyl)acetyl-CoA + H2O = (2-aminobenzoyl)acetate + CoA |
| Other name(s): |
pqsE (gene name) |
| Systematic name: |
(2-aminobenzoyl)acetyl-CoA hydrolase |
| Comments: |
The enzyme, characterized from the bacterium Pseudomonas aeruginosa, participates in the production of the signal molecule 2-heptyl-4(1H)-quinolone (HHQ). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Yu, S., Jensen, V., Seeliger, J., Feldmann, I., Weber, S., Schleicher, E., Haussler, S. and Blankenfeldt, W. Structure elucidation and preliminary assessment of hydrolase activity of PqsE, the Pseudomonas quinolone signal (PQS) response protein. Biochemistry 48 (2009) 10298–10307. [DOI] [PMID: 19788310] |
| 2. |
Drees, S.L. and Fetzner, S. PqsE of Pseudomonas aeruginosa acts as pathway-specific thioesterase in the biosynthesis of alkylquinolone signaling molecules. Chem. Biol. 22 (2015) 611–618. [DOI] [PMID: 25960261] |
|
| [EC 3.1.2.32 created 2016] |
| |
|
| |
|
Printable version