The Enzyme Database

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EC 3.1.1.8     
Accepted name: cholinesterase
Reaction: an acylcholine + H2O = choline + a carboxylate
Other name(s): pseudocholinesterase; butyrylcholine esterase; non-specific cholinesterase; choline esterase II (unspecific); benzoylcholinesterase; choline esterase; butyrylcholinesterase; propionylcholinesterase; anticholineesterase; BtChoEase
Systematic name: acylcholine acylhydrolase
Comments: Acts on a variety of choline esters and a few other compounds.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9001-08-5
References:
1.  Augustinsson, K.-B. Cholinesterases. A study in comparative enzymology. Acta Physiol. Scand. 15, Suppl. 2 (1948) .
2.  Augustinsson, K.-B. and Olsson, B. Esterases in the milk and blood plasma of swine. 1. Substrate specificity and electrophoresis studies. Biochem. J. 71 (1959) 477–484. [PMID: 13638253]
3.  Koelle, G.B. Cholinesterases of the tissues and sera of rabbits. Biochem. J. 53 (1953) 217–226. [PMID: 13032058]
4.  Nachmansohn, D. and Wilson, I.B. The enzymic hydrolysis and synthesis of acetylcholine. Adv. Enzymol. Relat. Subj. Biochem. 12 (1951) 259–339. [PMID: 14885021]
5.  Sawyer, C.H. Hydrolysis of choline esters by liver. Science 101 (1945) 385–386.
6.  Strelitz, F. Studies on cholinesterase. 4. Purification of pseudo-cholinesterase from horse serum. Biochem. J. 38 (1944) 86–88. [PMID: 16747753]
[EC 3.1.1.8 created 1961]
 
 


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