| EC |
3.1.1.53 |
| Accepted name: |
sialate O-acetylesterase |
| Reaction: |
N-acetyl-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate |
| Other name(s): |
N-acetylneuraminate acetyltransferase; sialate 9(4)-O-acetylesterase; sialidase |
| Systematic name: |
N-acyl-O-acetylneuraminate O-acetylhydrolase |
| Comments: |
Acts on free and glycosidically bound N-acetyl- or N-glycoloyl-neuraminic acid; acts mainly on the 4-O- and 9-O-acetyl groups. Also acts on some other O-acetyl esters, both cyclic and acyclic compounds, which are not sialic acids. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 89400-31-7 |
| References: |
| 1. |
Garcia-Sastre, A., Villar, E., Manuguerra, J.C., Hannoun, C. and Cabezas, J.A. Activity of influenza C virus O-acetylesterase with O-acetyl-containing compounds. Biochem. J. 273 (1991) 435–441. [PMID: 1991039] |
| 2. |
Shukla, A.K. and Schauer, R. High performance liquid chromatography of enzymes of sialic acid metabolism. Hoppe-Seyler's Z. Physiol. Chem. 363 (1982) 1039–1040. |
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| [EC 3.1.1.53 created 1984] |
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