The Enzyme Database

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EC 2.8.2.11     
Accepted name: galactosylceramide sulfotransferase
Reaction: 3′-phosphoadenylyl sulfate + a galactosylceramide = adenosine 3′,5′-bisphosphate + a galactosylceramidesulfate
Glossary: 3′-phosphoadenylyl sulfate = PAPS
Other name(s): GSase; 3′-phosphoadenosine-5′-phosphosulfate-cerebroside sulfotransferase; galactocerebroside sulfotransferase; galactolipid sulfotransferase; glycolipid sulfotransferase; glycosphingolipid sulfotransferase
Systematic name: 3′-phosphoadenylyl-sulfate:galactosylceramide 3′-sulfotransferase
Comments: Also acts on lactosylceramide.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9081-06-5
References:
1.  McKhann, G.M., Levy, R. and Ho, W. Metabolism of sulfatides. I. The effect of galactocerebrosides on the synthesis of sulfatides. Biochem. Biophys. Res. Commun. 20 (1965) 109–113. [PMID: 5850675]
2.  Sakakibara, N., Gasa, S., Kamio, K., Makita, A. and Koyanagi, T. Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma. Cancer Res. 49 (1989) 335–339. [PMID: 2562926]
[EC 2.8.2.11 created 1972, modified 1976]
 
 


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