The Enzyme Database

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EC 2.7.8.29     
Accepted name: L-serine-phosphatidylethanolamine phosphatidyltransferase
Reaction: L-1-phosphatidylethanolamine + L-serine = L-1-phosphatidylserine + ethanolamine
Other name(s): phosphatidylserine synthase 2; serine-exchange enzyme II; PTDSS2 (gene name)
Systematic name: L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase
Comments: This mammalian enzyme catalyses an exchange reaction in which the polar head group of phosphatidylethanolamine is replaced by L-serine.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Stone, S.J. and Vance, J.E. Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2. Biochem. J. 342 (1999) 57–64. [PMID: 10432300]
2.  Tomohiro, S., Kawaguti, A., Kawabe, Y., Kitada, S. and Kuge, O. Purification and characterization of human phosphatidylserine synthases 1 and 2. Biochem. J. 418 (2009) 421–429. [PMID: 19014349]
[EC 2.7.8.29 created 2010]
 
 


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