| EC |
2.7.7.1 |
| Accepted name: |
nicotinamide-nucleotide adenylyltransferase |
| Reaction: |
ATP + nicotinamide ribonucleotide = diphosphate + NAD+ |
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For diagram of NADP+ biosynthesis, click here |
| Other name(s): |
NAD+ pyrophosphorylase; adenosine triphosphate-nicotinamide mononucleotide transadenylase; ATP:NMN adenylyltransferase; diphosphopyridine nucleotide pyrophosphorylase; nicotinamide adenine dinucleotide pyrophosphorylase; nicotinamide mononucleotide adenylyltransferase; NMN adenylyltransferase |
| Systematic name: |
ATP:nicotinamide-nucleotide adenylyltransferase |
| Comments: |
Nicotinate nucleotide can also act as acceptor. See also EC 2.7.7.18 nicotinate-nucleotide adenylyltransferase. |
| Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9032-70-6 |
| References: |
| 1. |
Atkinson, M.R., Jackson, J.F. and Morton, R.K. Nicotinamide mononucleotide adenylyltransferase of pig-liver nuclei. The effects of nicotinamide mononucleotide concentration and pH on dinucleotide synthesis. Biochem. J. 80 (1961) 318–323. [PMID: 13684981] |
| 2. |
Dahmen, W., Webb, B. and Preiss, J. The deamido-diphosphopyridine nucleotide and diphosphopyridine nucleotide pyrophosphorylases of Escherichia coli and yeast. Arch. Biochem. Biophys. 120 (1967) 440–450. [DOI] [PMID: 4291828] |
| 3. |
Kornberg, A. and Pricer, W.E. Enzymatic cleavage of diphosphopyridine nucleotide with radioactive pyrophosphate. J. Biol. Chem. 191 (1951) 535–541. [PMID: 14861199] |
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| [EC 2.7.7.1 created 1961] |
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