The Enzyme Database

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EC 2.7.6.2     
Accepted name: thiamine diphosphokinase
Reaction: ATP + thiamine = AMP + thiamine diphosphate
Glossary: thiamine diphosphate = 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-diphosphoethyl)-4-methyl-1,3-thiazolium
Other name(s): thiamin kinase; thiamine pyrophosphokinase; ATP:thiamin pyrophosphotransferase; thiamin pyrophosphokinase; thiamin pyrophosphotransferase; thiaminokinase; thiamin:ATP pyrophosphotransferase; TPTase
Systematic name: ATP:thiamine diphosphotransferase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9026-24-8
References:
1.  Leuthardt, F. and Nielsen, H. Phosphorylation biologique de la thiamine. Helv. Chim. Acta 35 (1952) 1196–1209.
2.  Shimazono, N., Mano, Y., Tanaka, R. and Kajiro, Y. Mechanism of transpyrophosphorylation with thiamine pyrophosphokinase. J. Biochem. (Tokyo) 46 (1959) 959–961.
3.  Steyn-Parvé, E.P. Partial purification and properties of thiaminokinase from yeast. Biochim. Biophys. Acta 8 (1952) 310–324. [PMID: 14934742]
[EC 2.7.6.2 created 1961]
 
 


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