The Enzyme Database

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EC 2.7.4.4     
Accepted name: nucleoside-phosphate kinase
Reaction: ATP + nucleoside phosphate = ADP + nucleoside diphosphate
For diagram of GTP biosynthesis, click here
Other name(s): NMP-kinase
Systematic name: ATP:nucleoside-phosphate phosphotransferase
Comments: Many nucleotides can act as acceptors; other nucleoside triphosphates can act instead of ATP.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, MetaCyc, CAS registry number: 9026-50-0
References:
1.  Gibson, D.M., Ayengar, P. and Sanadi, D.R. Transphosphorylations between nucleoside phosphates. Biochim. Biophys. Acta 21 (1956) 86–91. [PMID: 13363863]
2.  Heppel, L.A., Strominger, J.L. and Maxwell, E.S. Nucleoside monophosphate kinases. II. Transphosphorylation between adenosine monophosphate and nucleotide triphosphate. Biochim. Biophys. Acta 32 (1959) 422–430. [PMID: 14401179]
3.  Lieberman, I., Kornberg, A. and Simms, E.S. Enzymatic synthesis of nucleotide diphosphates and triphosphates. J. Biol. Chem. 215 (1955) 429–440. [PMID: 14392176]
4.  Noda, L. Nucleoside triphosphate-nucleoside monophosphokinases. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds), The Enzymes, 2nd edn, vol. 6, Academic Press, New York, 1962, pp. 139–149.
[EC 2.7.4.4 created 1961]
 
 


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