The Enzyme Database

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EC 2.7.4.15     
Accepted name: thiamine-diphosphate kinase
Reaction: ATP + thiamine diphosphate = ADP + thiamine triphosphate
For diagram of thiamine diphosphate biosynthesis, click here
Glossary: thiamine diphosphate = 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-diphosphoethyl)-4-methyl-1,3-thiazolium
Other name(s): ATP:thiamin-diphosphate phosphotransferase; TDP kinase; thiamin diphosphate kinase; thiamin diphosphate phosphotransferase; thiamin pyrophosphate kinase; thiamine diphosphate kinase; protein bound thiamin diphosphate:ATP phosphoryltransferase
Systematic name: ATP:thiamine-diphosphate phosphotransferase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9075-79-0
References:
1.  Itokawa, Y. and Cooper, J.R. The enzymatic synthesis of triphosphothiamin. Biochim. Biophys. Acta 158 (1968) 180–182. [PMID: 5661031]
2.  Kikuchi, M. and Ikawa, T. Presence of an enzyme mediating transfer of phosphate from thiamine triphosphate to ADP in germinating maize. Bot. Mag. (Tokyo) 97 (1984) 193–205.
[EC 2.7.4.15 created 1972]
 
 


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