The Enzyme Database

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EC 2.7.1.214     
Accepted name: C7-cyclitol 7-kinase
Reaction: (1) ATP + valienone = ADP + valienone 7-phosphate
(2) ATP + validone = ADP + validone 7-phosphate
Glossary: valienone = (4R,5S,6R)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-one
validone = (2R,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexan-1-one
Other name(s): valC (gene name); vldC (gene name)
Systematic name: ATP:C7-cyclitol 7-phosphotransferase
Comments: The enzyme, characterized from the bacterium Streptomyces hygroscopicus var. jinggangensis, is involved in the biosynthesis of the antifungal agent validamycin A.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Minagawa, K., Zhang, Y., Ito, T., Bai, L., Deng, Z. and Mahmud, T. ValC, a new type of C7-Cyclitol kinase involved in the biosynthesis of the antifungal agent validamycin A. Chembiochem 8 (2007) 632–641. [PMID: 17335096]
[EC 2.7.1.214 created 2016]
 
 


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