The Enzyme Database

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EC 2.7.1.161     
Accepted name: CTP-dependent riboflavin kinase
Reaction: CTP + riboflavin = CDP + FMN
Other name(s): Methanocaldococcus jannaschii Mj0056; Mj0056
Systematic name: CTP:riboflavin 5′-phosphotransferase
Comments: This archaeal enzyme differs from EC 2.7.1.26, riboflavin kinase, in using CTP as the donor nucleotide. UTP, but not ATP or GTP, can also act as a phosphate donor but it is at least an order of magnitude less efficient than CTP.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
References:
1.  Ammelburg, M., Hartmann, M.D., Djuranovic, S., Alva, V., Koretke, K.K., Martin, J., Sauer, G., Truffault, V., Zeth, K., Lupas, A.N. and Coles, M. A CTP-dependent archaeal riboflavin kinase forms a bridge in the evolution of cradle-loop barrels. Structure 15 (2007) 1577–1590. [PMID: 18073108]
[EC 2.7.1.161 created 2008]
 
 


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